Van Asperen P P, Kemp A S, Mellis C M
Clin Allergy. 1984 Nov;14(6):525-32. doi: 10.1111/j.1365-2222.1984.tb02239.x.
We examined the relationship of diet to the development of atopic manifestations in a group of infants with an immediate family history of atopy, followed prospectively from birth for up to 20 months of age. There was no relationship between the development of atopic dermatitis, rhinitis and wheeze and either 2 or 4 months exclusive breast feeding, or the introduction of cow's milk or solids in the first 4 months of life. In addition there was no relationship between the introduction of milk, egg or wheat into the diet and the development of skin-test positivity to these foods. In fact, five infants developed positive skin tests to the food prior to its introduction into the diet, suggesting exposure via maternal breast milk. Thus we have been unable to show a protective effect of either breast feeding or cow's milk or solid avoidance on the development of atopic disease in infancy.
我们对一组有特应性疾病家族史的婴儿进行了前瞻性研究，从出生一直追踪到20个月大，以调查饮食与特应性表现发展之间的关系。在特应性皮炎、鼻炎和喘息的发展与出生后2个月或4个月纯母乳喂养，或在生命的前4个月引入牛奶或固体食物之间，没有发现相关性。此外，在饮食中引入牛奶、鸡蛋或小麦与对这些食物皮肤试验呈阳性的发展之间也没有相关性。事实上，有5名婴儿在饮食中引入某种食物之前，对该食物的皮肤试验就呈阳性，这表明是通过母乳接触到了这些食物。因此，我们未能证明母乳喂养、避免牛奶或固体食物对婴儿期特应性疾病的发展有保护作用。
