棒状噬菌体的热诱导突变体
Heat-inducible mutants of corynebacteriophage.
作者信息
Groman N, Laird W
出版信息
J Virol. 1977 Sep;23(3):587-91. doi: 10.1128/JVI.23.3.587-591.1977.
Abstract
Heat-inducible mutants of temperate cornebacteriophage beta and gamma, called temperature-sensitive repression (tsr) mutants, were isolated and characterized. Lysogens carrying these mutants were induced at 38 degrees C, produced a normal or slightly increased yield of phage, and underwent extensive lysis at this temperature. In some cases mutation to heat inducibility had altered the UV inducibility of the phage, the changes ranging from loss to enhancement of this trait. Complementation tests showed that all five beta-tsr strains had mutated in the same cistron and suggested that these mutations were in the gene responsible for repressor production.
摘要
分离并鉴定了温和型棒状噬菌体β和γ的热诱导突变体，即温度敏感型阻遏（tsr）突变体。携带这些突变体的溶原菌在38℃下被诱导，产生正常或略有增加的噬菌体产量，并在此温度下发生广泛裂解。在某些情况下，热诱导突变改变了噬菌体的紫外线诱导性，这种变化范围从该特性的丧失到增强。互补试验表明，所有五个β-tsr菌株都在同一顺反子中发生了突变，并表明这些突变位于负责阻遏物产生的基因中。
相似文献
1
Heat-inducible mutants of corynebacteriophage.棒状噬菌体的热诱导突变体
J Virol. 1977 Sep;23(3):587-91. doi: 10.1128/JVI.23.3.587-591.1977.
2
Control of corynebacteriophage reproduction by heteroimmune repression.通过异源免疫抑制控制棒状噬菌体的繁殖
J Virol. 1978 Oct;28(1):28-33. doi: 10.1128/JVI.28.1.28-33.1978.
3
Temperature-sensitive mutants of toxinogenic corynebacteriophage beta. I. Genetics.产毒素棒状噬菌体β的温度敏感突变体。I. 遗传学
Virology. 1973 Oct;55(2):347-56. doi: 10.1016/0042-6822(73)90174-8.
4
Genetic analysis of tox+ and tox- bacteriophages of Corynebacterium diphtheriae.白喉棒状杆菌产毒和无毒噬菌体的遗传分析。
J Virol. 1969 Jun;3(6):586-98. doi: 10.1128/JVI.3.6.586-598.1969.
5
Genetic elements novel for Corynebacterium diphtheriae: specialized transducing elements and transposons.白喉棒状杆菌的新型遗传元件：特异性转导元件和转座子。
J Bacteriol. 1981 Oct;148(1):143-52. doi: 10.1128/jb.148.1.143-152.1981.
6
Temperate coliphage HK022. Clear plaque mutants and preliminary vegetative map.温和型大肠杆菌噬菌体HK022。透明噬菌斑突变体及初步的营养期图谱。
Jpn J Microbiol. 1976 Oct;20(5):385-96. doi: 10.1111/j.1348-0421.1976.tb01004.x.
7
Bacteriophage production by doubly lysogenic Corynebacterium diphtheriae.双溶源性白喉棒状杆菌产生噬菌体
J Virol. 1977 Sep;23(3):592-8. doi: 10.1128/JVI.23.3.592-598.1977.
8
Recombination-deficient mutants of Bacillus subtilis.枯草芽孢杆菌的重组缺陷型突变体。
J Bacteriol. 1976 Feb;125(2):489-500. doi: 10.1128/jb.125.2.489-500.1976.
9
Prophage map of converting corynebacteriophage beta.转化棒状噬菌体β的原噬菌体图谱。
J Virol. 1976 Jul;19(1):208-19. doi: 10.1128/JVI.19.1.208-219.1976.
10
Repair deficiency, mutator activity, and thermal prophage inducibility in dna-8132 strains of Bacillus subtilis.枯草芽孢杆菌dna - 8132菌株中的修复缺陷、诱变活性和热原噬菌体诱导性
J Bacteriol. 1976 Jun;126(3):1037-41. doi: 10.1128/jb.126.3.1037-1041.1976.
引用本文的文献
1
Gene responsible for superinfection exclusion of heteroimmune corynebacteriophage.负责异源免疫棒状噬菌体超感染排除的基因。
J Virol. 1982 Apr;42(1):49-54. doi: 10.1128/JVI.42.1.49-54.1982.
2
Superinfection exclusion by heteroimmune corynebacteriophages.异源免疫棒状噬菌体的超感染排除
J Virol. 1980 Nov;36(2):526-32. doi: 10.1128/JVI.36.2.526-532.1980.
3
Identification of deoxyribonucleic acid restriction fragments of beta-converting corynebacteriophages that carry the gene for diphtheria toxin.携带白喉毒素基因的β-转化棒状噬菌体的脱氧核糖核酸限制性片段的鉴定。
J Bacteriol. 1981 Oct;148(1):153-62. doi: 10.1128/jb.148.1.153-162.1981.
4
Physical mapping of beta-converting and gamma-nonconverting corynebacteriophage genomes.β-转化和γ-非转化棒状噬菌体基因组的物理图谱
J Bacteriol. 1981 Oct;148(1):131-42. doi: 10.1128/jb.148.1.131-142.1981.
5
DNA relationships among some tox-bearing corynebacteriophages.一些携带毒素的棒状噬菌体之间的DNA关系。
Infect Immun. 1985 Sep;49(3):679-84. doi: 10.1128/iai.49.3.679-684.1985.
6
Isolation and characterization of extragenic suppressor strains of Corynebacterium diphtheriae.
J Bacteriol. 1978 Dec;136(3):1135-42. doi: 10.1128/jb.136.3.1135-1142.1978.
7
Control of corynebacteriophage reproduction by heteroimmune repression.通过异源免疫抑制控制棒状噬菌体的繁殖
J Virol. 1978 Oct;28(1):28-33. doi: 10.1128/JVI.28.1.28-33.1978.
本文引用的文献
1
[On a thermosensitive repression system in the Escherichia coli lambda bacteriophage].[关于大肠杆菌λ噬菌体中的热敏抑制系统]
C R Hebd Seances Acad Sci. 1962 Feb 19;254:1517-9.
2
Second locus of bacteriophage P22 necessary for the maintenance of lysogeny.噬菌体P22维持溶原性所必需的第二个位点。
J Virol. 1968 Oct;2(10):992-8. doi: 10.1128/JVI.2.10.992-998.1968.
3
Temperature-sensitive regulation system of prophage lambda induction.噬菌体λ诱导的温度敏感调节系统
J Mol Biol. 1967 Jan 28;23(2):217-24. doi: 10.1016/s0022-2836(67)80029-9.
4
Studies of heat-inducible lambda phage. IV. Conversion of host phenotype by a defective prophage.热诱导λ噬菌体的研究。IV. 缺陷原噬菌体对宿主表型的转化
Virology. 1967 Apr;31(4):643-56. doi: 10.1016/0042-6822(67)90193-6.
5
Cohesive sites on the deoxyribonucleic acids from several temperate coliphages.几种温和型大肠杆菌噬菌体脱氧核糖核酸上的粘性位点
J Mol Biol. 1966 Jun;17(2):343-57. doi: 10.1016/s0022-2836(66)80146-8.
6
Studies of heat-inducible lambda bacteriophage. I. Order of genetic sites and properties of mutant prophages.热诱导λ噬菌体的研究。I. 遗传位点顺序及突变原噬菌体的特性
J Mol Biol. 1966 Mar;16(1):149-63. doi: 10.1016/s0022-2836(66)80269-3.
7
8
Temperature-sensitive mutants of toxinogenic corynebacteriophage beta. I. Genetics.产毒素棒状噬菌体β的温度敏感突变体。I. 遗传学
Virology. 1973 Oct;55(2):347-56. doi: 10.1016/0042-6822(73)90174-8.
9
Isolation and characterization of tox mutants of corynebacteriophage beta.β-棒状杆菌噬菌体tox突变体的分离与鉴定
J Virol. 1976 Jul;19(1):220-27. doi: 10.1128/JVI.19.1.220-227.1976.
10
Prophage map of converting corynebacteriophage beta.转化棒状噬菌体β的原噬菌体图谱。
J Virol. 1976 Jul;19(1):208-19. doi: 10.1128/JVI.19.1.208-219.1976.
Zotero 插件