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经导管主动脉瓣植入术治疗肝硬化合并肝细胞癌患者感染性心内膜炎所致重度主动脉瓣关闭不全:一种新的适应证

Transcatheter Aortic Valve Implantation for Severe Aortic Insufficiency Due to Infective Endocarditis in a Patient with Cirrhosis and Hepatocellular Cancer: A Novel Indication.

作者信息

Abujalala Salem, Ede Huseyin, Abdullatef Waleed Khalid, Al-Hijji Mohammed Ahmad

机构信息

Department of Cardiology, Hamad Medical Corporation, Heart Hospital, Doha, Qatar.

出版信息

Heart Views. 2025 Jan-Mar;26(1):43-47. doi: 10.4103/heartviews.heartviews_139_23. Epub 2025 Jul 16.

Abstract

Infective endocarditis (IE) of the native aortic valve (AV) secondary to is subacute, a highly destructive pathology leading to aortic regurgitation (AR) and severe cardiac complications such as progressively deteriorating heart failure. In these cases, valvular correction with surgery may not be the optimal option because of multiple chronic illnesses and the use of medications. Although transcatheter AV implantation (TAVI) is a well-known, established alternative method to surgical replacement in patients with severe aortic stenosis, it can be a good alternative in patients with severe AR in whom valvular surgery is not an option due to comorbidities. Here, we presented a case of TAVI in a patient with cirrhosis, hepatocellular cancer, and symptomatic severe AR due to IE.

摘要

继发于[具体病因未提及]的原发性主动脉瓣(AV)感染性心内膜炎(IE)为亚急性,是一种极具破坏性的病理状态,可导致主动脉反流(AR)及严重心脏并发症,如心力衰竭进行性加重。在这些病例中,由于存在多种慢性疾病及正在使用药物,手术进行瓣膜矫正可能并非最佳选择。尽管经导管主动脉瓣植入术(TAVI)是治疗严重主动脉瓣狭窄患者的一种广为人知且成熟的外科置换替代方法,但对于因合并症而无法进行瓣膜手术的严重AR患者,它也可能是一种不错的选择。在此,我们报告了一例因IE导致肝硬化、肝细胞癌且有症状性严重AR的患者接受TAVI治疗的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/12370093/c19b878261e0/HV-26-43-g001.jpg

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