Kumar A, Bhat A, Gupta D K, Goel A, Malaviya A N
Clin Exp Rheumatol. 1985 Oct-Dec;3(4):337-9.
Acute hypersensitivity pneumonitis is not a known side effect of D-penicillamine. Also, there are only a few reports of cholestatic hepatitis caused by this drug. The present report describes a case of rheumatoid arthritis where these manifestations appeared in the same patient ten days after the institution of D-penicillamine therapy. The etiological relationship with the drug was established, inadvertantly, by its accidental intake by the patient 5 months later with the reproduction of the same manifestations.
急性过敏性肺炎并非青霉胺已知的副作用。此外，关于该药物引起胆汁淤积性肝炎的报道也仅有几例。本报告描述了一例类风湿关节炎患者，在开始使用青霉胺治疗十天后出现了上述两种表现。五个月后患者意外再次服用该药，相同表现再次出现，从而意外地确定了这些表现与该药物的因果关系。
