Barzilai D, Dickstein G, Enat R, Bassan H, Lichtig C, Gellei B
Ann Rheum Dis. 1978 Feb;37(1):98-100. doi: 10.1136/ard.37.1.98.
D-penicillamine is not generally considered to cause hepatic damage. Cholestatic jaundice developed in a patient with rheumatoid arthritis 4 weeks after penicillamine was added to his regimen, and he died in acute renal failure. The probability that penicillamine caused the cholestasis is discussed.
一般认为D-青霉胺不会引起肝损伤。一名类风湿性关节炎患者在其治疗方案中加入青霉胺4周后出现胆汁淤积性黄疸,并死于急性肾衰竭。本文讨论了青霉胺导致胆汁淤积的可能性。