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青霉胺引起的胆汁淤积性黄疸。

Cholestatic jaundice caused by D-penicillamine.

作者信息

Barzilai D, Dickstein G, Enat R, Bassan H, Lichtig C, Gellei B

出版信息

Ann Rheum Dis. 1978 Feb;37(1):98-100. doi: 10.1136/ard.37.1.98.

DOI:10.1136/ard.37.1.98
PMID:629612
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1000201/
Abstract

D-penicillamine is not generally considered to cause hepatic damage. Cholestatic jaundice developed in a patient with rheumatoid arthritis 4 weeks after penicillamine was added to his regimen, and he died in acute renal failure. The probability that penicillamine caused the cholestasis is discussed.

摘要

一般认为D-青霉胺不会引起肝损伤。一名类风湿性关节炎患者在其治疗方案中加入青霉胺4周后出现胆汁淤积性黄疸,并死于急性肾衰竭。本文讨论了青霉胺导致胆汁淤积的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c10b/1000201/79021decdfda/annrheumd00083-0108-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c10b/1000201/a1e6b7c61c55/annrheumd00083-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c10b/1000201/79021decdfda/annrheumd00083-0108-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c10b/1000201/a1e6b7c61c55/annrheumd00083-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c10b/1000201/79021decdfda/annrheumd00083-0108-b.jpg

相似文献

1
Cholestatic jaundice caused by D-penicillamine.青霉胺引起的胆汁淤积性黄疸。
Ann Rheum Dis. 1978 Feb;37(1):98-100. doi: 10.1136/ard.37.1.98.
2
Cholestatic jaundice associated with D-penicillamine therapy.
Scand J Rheumatol. 1985;14(3):303-6. doi: 10.3109/03009748509100411.
3
Fatal cholestatic hepatitis caused by D-penicillamine.
Br J Rheumatol. 1994 Aug;33(8):770-3. doi: 10.1093/rheumatology/33.8.770.
4
A case of cholestatic hepatitis associated with D-penicillamine therapy for rheumatoid arthritis.
Int J Clin Pharmacol Res. 1985;5(1):35-8.
5
[Liver complications caused by D-penicillamine. Apropos of a case].
Rev Rhum Mal Osteoartic. 1986 Jan;53(1):21-3.
6
Selected adverse reactions of D-penicillamine.
Clin Invest Med. 1984;7(1):73-6.
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Cholestasis associated with D-penicillamine therapy: case report and review of the literature.
Arthritis Rheum. 1981 Mar;24(3):554-6. doi: 10.1002/art.1780240317.
8
[Intrahepatic cholestasis following treatment with D-penicillamine and indomethacin].[D-青霉胺和吲哚美辛治疗后发生的肝内胆汁淤积]
Med Welt. 1976 Jan 23;27(4):172-3.
9
Cholestasis associated with d-penicillamine therapy for rheumatoid arthritis.与用于类风湿关节炎的青霉胺治疗相关的胆汁淤积。
Can Med Assoc J. 1979 Apr 21;120(8):965-6.
10
D-penicillamine-induced acute hypersensitivity pneumonitis and cholestatic hepatitis in a patient with rheumatoid arthritis.青霉胺诱发的类风湿关节炎患者急性过敏性肺炎和胆汁淤积性肝炎
Clin Exp Rheumatol. 1985 Oct-Dec;3(4):337-9.

引用本文的文献

1
Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis.类风湿关节炎患者使用青霉胺相关的肝毒性。
Ann Rheum Dis. 1980 Apr;39(2):152-4. doi: 10.1136/ard.39.2.152.
2
Clinical associations between arthritis and liver disease.关节炎与肝脏疾病之间的临床关联。
Ann Rheum Dis. 1982 Jun;41(3):295-307. doi: 10.1136/ard.41.3.295.
3
Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis.青霉胺治疗类风湿关节炎导致的致命性再生障碍性贫血和肝毒性。

本文引用的文献

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Serum transaminases during salicylate therapy.水杨酸盐治疗期间的血清转氨酶
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Serum transaminases and salicylate therapy.血清转氨酶与水杨酸盐疗法
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Aspirin-induced hepatotoxicity in patients with systemic lupus erythematosus.系统性红斑狼疮患者的阿司匹林诱发肝毒性
Ann Intern Med. 1974 Jan;80(1):1-8. doi: 10.7326/0003-4819-80-1-1.
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Salicylate hepatotoxicity in patients with juvenile rheumatoid arthritis.青少年类风湿关节炎患者的水杨酸盐肝毒性
Arthritis Rheum. 1973 Jan-Feb;16(1):1-9. doi: 10.1002/art.1780160102.
10
Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis.与青霉胺治疗类风湿关节炎相关的重症肌无力。
Br Med J. 1975 Mar 15;1(5958):600-2. doi: 10.1136/bmj.1.5958.600.