Blanco Flórez Pilar Rocio, Páez Jennifer Orozco
Research Department, Corporación para la educación y la investigación Medlaser (CEIM), Santa Marta, Colombia.
Química analítica y Biomedicina research Group, Faculty of Pharmaceutical Sciences, Universidad de Cartagena, Cartagena, Colombia.
J Lasers Med Sci. 2025 Jun 29;16:e18. doi: 10.34172/jlms.2025.18. eCollection 2025.
Osteonecrosis causes the death of bone tissue due to insufficient blood flow, which disrupts the supply of oxygen and nutrients, compromising the structural integrity of the bone. The jaws are particularly vulnerable due to their high bone turnover and vascularization. This study aimed to present the complex case of a patient diagnosed with maxillary osteonecrosis associated with osteomyelitis, treated exclusively with laser therapy. We present the case of a 62-year-old male patient with maxillary osteonecrosis associated with osteomyelitis, manifested by an oroantral fistula located in the upper jaw. The treatment consisted of various laser therapy modalities, starting with the surgical phase on hard tissue for the excision of the necrotic bone (Er,Cr:YSGG 2780 nm laser), followed by photodynamic therapy (650 nm diode laser) for wound disinfection and intravascular laser irradiation of blood (ILIB) therapy (880 nm diode laser) in each session. The combination of different laser wavelengths was effective for the treatment of osteonecrosis.
骨坏死是由于血流不足导致骨组织死亡，这会扰乱氧气和营养物质的供应，损害骨骼的结构完整性。颌骨因其高骨转换率和血管化程度而特别脆弱。本研究旨在介绍一例被诊断为与骨髓炎相关的上颌骨坏死患者的复杂病例，该患者仅接受激光治疗。我们报告了一例62岁男性患者，患有与骨髓炎相关的上颌骨坏死，表现为上颌的口腔上颌窦瘘。治疗包括各种激光治疗方式，首先是在硬组织上进行手术切除坏死骨（铒铬：钇-钪-镓-石榴石2780纳米激光），随后进行光动力治疗（650纳米二极管激光）以进行伤口消毒，并在每次治疗中进行血液血管内激光照射（ILIB）治疗（880纳米二极管激光）。不同激光波长的组合对骨坏死的治疗有效。
