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体力活动与儿童癌症:现状与未来方向

Physical Activity and Childhood Cancer: Present Status and Future Directions.

作者信息

Caru Maxime, Dandekar Smita, Schmitz Kathryn H

机构信息

Division of Hematology and Oncology, Department of Pediatrics, Pennsylvania State Health Children's Hospital, Hershey, PA, USA (MC, SD).

Department of Public Health Sciences, Penn State University College of Medicine, Hershey, PA, USA (MC).

出版信息

Am J Lifestyle Med. 2025 Aug 20:15598276251368342. doi: 10.1177/15598276251368342.

DOI:10.1177/15598276251368342
PMID:40852085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12367733/
Abstract

In children diagnosed with cancer, both physical and mental health are significantly impacted. Physical activity has emerged as a promising non-pharmacological intervention to improve both physical and psychosocial wellbeing, with growing evidence supporting its role in improving survivorship. Notably, pediatric patients who engage in regular physical activity demonstrate reduced all-cause mortality, particularly among female patients. Current research in physical activity and pediatric oncology aims to further improve mental and physical health, cardiac function, survival outcomes, and overall care. This paper provides an overview of the current state and future directions of the field, emphasizing the need for stronger evidence to support the integration of physical activity as a standard component of care. As the field advances, coordinated efforts among clinicians, researchers, and policy stakeholders will be critical to ensure equitable access to regular physical activity support for all pediatric cancer patients.

摘要

在被诊断患有癌症的儿童中,身心健康都会受到显著影响。体育活动已成为一种有前景的非药物干预措施,可改善身体和心理社会健康,越来越多的证据支持其在改善癌症 survivorship 方面的作用。值得注意的是,经常进行体育活动的儿科患者全因死亡率降低,尤其是女性患者。目前关于体育活动与儿科肿瘤学的研究旨在进一步改善身心健康、心脏功能、生存结果和整体护理。本文概述了该领域的现状和未来方向,强调需要更有力的证据来支持将体育活动纳入标准护理组成部分。随着该领域的发展,临床医生、研究人员和政策利益相关者之间的协调努力对于确保所有儿科癌症患者都能公平获得定期体育活动支持至关重要。

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本文引用的文献

1
The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers: A Review.儿童肿瘤学组关于儿童、青少年和青年癌症幸存者的长期随访指南:综述
JAMA Oncol. 2025 May 1;11(5):544-553. doi: 10.1001/jamaoncol.2024.6812.
2
Implementing a behavioral physical activity program in children and adolescent survivors of childhood cancer: a pilot randomized controlled trial.在儿童期癌症幸存者中实施行为性体力活动方案:一项试点随机对照试验。
J Behav Med. 2024 Oct;47(5):792-803. doi: 10.1007/s10865-024-00497-z. Epub 2024 May 12.
3
Behavioral physical activity intervention coupled with standard post-cancer directed treatment care to mitigate chronic pain in childhood cancer survivors: A protocol for a single-center, pilot randomized controlled trial.行为体育活动干预联合标准的癌症后定向治疗护理以减轻儿童癌症幸存者的慢性疼痛:一项单中心、试点随机对照试验方案。
Contemp Clin Trials Commun. 2023 Oct 5;36:101216. doi: 10.1016/j.conctc.2023.101216. eCollection 2023 Dec.
4
Echocardiographic Parameters Associated With Cardiorespiratory Fitness and Physical Activity in Childhood Acute Lymphoblastic Leukemia Survivors.与儿童期急性淋巴细胞白血病幸存者心肺适能和身体活动相关的超声心动图参数。
J Phys Act Health. 2023 Oct 4;20(12):1152-1161. doi: 10.1123/jpah.2023-0100. Print 2023 Dec 1.
5
Effects of Exercise and Physical Activity Levels on Childhood Cancer: An Umbrella Review.运动和身体活动水平对儿童癌症的影响:一项系统性综述
Healthcare (Basel). 2023 Mar 10;11(6):820. doi: 10.3390/healthcare11060820.
6
Cardiorespiratory Fitness and Cardiac Magnetic Resonance Imaging in Childhood Acute Lymphoblastic Leukemia Survivors.儿童期急性淋巴细胞白血病幸存者的心肺适应能力和心脏磁共振成像。
J Phys Act Health. 2023 Mar 27;20(6):522-530. doi: 10.1123/jpah.2022-0179. Print 2023 Jun 1.
7
Cancer-related fatigue: scoping review to synthesize a definition for childhood cancer survivors.癌症相关疲劳:为儿童癌症幸存者综合定义的范围综述。
Support Care Cancer. 2023 Mar 24;31(4):231. doi: 10.1007/s00520-023-07690-x.
8
Chronic pain in children and adolescents diagnosed with cancer: the challenge of mitigating the pain and the potential of integrating exercise into pain management.儿童和青少年癌症患者的慢性疼痛:缓解疼痛的挑战和将运动融入疼痛管理的潜力。
Support Care Cancer. 2023 Mar 23;31(4):228. doi: 10.1007/s00520-023-07695-6.
9
The pediatric oncology exercise field speeds up to address important issues regarding chemotherapy-related cardiotoxicity.儿科肿瘤学领域正在加速行动,以解决与化疗相关的心脏毒性的重要问题。
Front Pediatr. 2022 Oct 14;10:998337. doi: 10.3389/fped.2022.998337. eCollection 2022.
10
Perceived barriers and facilitators to physical activity in childhood cancer survivors and their parents: A large-scale interview study from the International PACCS Study.儿童癌症幸存者及其父母对身体活动的感知障碍和促进因素:来自国际 PACCS 研究的大规模访谈研究。
Pediatr Blood Cancer. 2023 Jan;70(1):e30056. doi: 10.1002/pbc.30056. Epub 2022 Oct 17.