Arnold-Vangsted Andreas, Ilginis Tomas, Folke Kiilgaard Jens, Heegaard Steffen, Faber Carsten
Department of Ophthalmology, Rigshospitalet, Glostrup, Denmark.
Eye Pathology Section, Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Am J Ophthalmol Case Rep. 2025 Jul 8;39:102380. doi: 10.1016/j.ajoc.2025.102380. eCollection 2025 Sep.
To describe a case of vitreoretinal lymphoma with unilateral vascular involvement.
A 80-year-old male with recurrent amaurosis fugax (AF) in the left eye was seen in the ophthalmological department. During a period of seven months the patient developed central vein occlusion (CRVO) and later the panuveitis suspected to be acute retinal necrosis (ARN) before being diagnosed with vitreoretinal lymphoma (VRL). The patient preferred enucleation as treatment which allowed thorough histological examination revealing Epstein Barr virus-associated vitreoretinal lymphoma.
Vascular involvement with AF and CRVO is yet to be described in relation to VRL. This case-study underlines the critical importance of considering VRL when the clinical course deviates from the expected.
描述一例伴有单侧血管受累的玻璃体视网膜淋巴瘤病例。
一名80岁男性因左眼反复出现一过性黑矇（AF）就诊于眼科。在七个月的时间里，患者先后出现中央静脉阻塞（CRVO），随后疑似急性视网膜坏死（ARN）的全葡萄膜炎，最终被诊断为玻璃体视网膜淋巴瘤（VRL）。患者选择眼球摘除术作为治疗方法，这使得通过彻底的组织学检查发现了与爱泼斯坦-巴尔病毒相关的玻璃体视网膜淋巴瘤。
AF和CRVO与VRL相关的血管受累情况此前尚未见报道。本病例研究强调，当临床病程偏离预期时，考虑VRL的至关重要性。
