Suppr超能文献

当代数字灌注下颌下腺造影术的临床应用

Clinical Utility of Contemporary Digital Infusion Submandibular Sialography.

作者信息

Molotkova Evgeniya, Wenzel Piper, Sylte Jeff, Fain Sean, Maley Joan, Thorpe Ryan, Hoffman Henry

机构信息

Department of Otolaryngology University of Iowa Iowa City Iowa USA.

Department of Radiology University of Iowa Iowa City Iowa USA.

出版信息

Laryngoscope Investig Otolaryngol. 2025 Aug 21;10(4):e70248. doi: 10.1002/lio2.70248. eCollection 2025 Aug.

Abstract

OBJECTIVES

Contemporary sialography couples mechanical ductal dilation with hydrodilation and utilizes iodinated contrast with antimicrobial properties to generate diagnostic data. This procedure has been reported to have therapeutic value that has not been investigated in a large contemporary series. This study examines the therapeutic value of diagnostic digital infusion submandibular sialography.

METHODS

Retrospective chart review of a consecutive series of submandibular sialograms from April 2008 to November 2024, focusing on symptomatic response to sialography.

RESULTS

Review identified 135 submandibular sialograms with follow-up addressing post-study symptom assessment available in 67. Indications for sialography in this group included pain (6/67), swelling (23/67), or both (38/67). Symptomatic improvement following sialography was reported in 67% of cases (45/67). Those reporting initial complete relief of symptoms rarely (15%) required additional treatment during the follow-up period ( = 0.019). The radiographic diagnosis of a distal stricture was associated with a higher rate of symptom improvement (78%) when compared to those without a distal stricture (57%) ( = 0.049). Among patients in this cohort, the median effective radiation dose (1.94 mSv) for the CT imaging preceding sialography ( = 39) was significantly greater than that calculated radiation dose (0.14 mSv) for one-gland sialography ( = 42) ( < 0.001).

CONCLUSION

Diagnostic submandibular sialography is often therapeutic and is performed with limited radiation exposure. Prospective study is ongoing to provide more detailed evaluation of the therapeutic impact of this procedure.

LEVEL OF EVIDENCE

摘要

目的

当代涎管造影术将机械性导管扩张与水扩张相结合,并使用具有抗菌特性的碘化造影剂来生成诊断数据。据报道,该操作具有治疗价值,但尚未在大型当代系列研究中进行探究。本研究旨在探讨数字化灌注诊断性下颌下腺涎管造影术的治疗价值。

方法

回顾性分析2008年4月至2024年11月连续一系列下颌下腺涎管造影病例,重点关注涎管造影后的症状反应。

结果

回顾发现135例下颌下腺涎管造影病例,其中67例有研究后症状评估的随访记录。该组涎管造影的指征包括疼痛(6/67)、肿胀(23/67)或两者皆有(38/67)。67%的病例(45/67)报告涎管造影后症状有所改善。那些报告症状最初完全缓解的患者在随访期间很少(15%)需要额外治疗(P = 0.019)。与无远端狭窄的患者(57%)相比,远端狭窄的影像学诊断与更高的症状改善率(78%)相关(P = 0.049)。在该队列患者中,涎管造影前CT成像的中位有效辐射剂量(1.94 mSv,n = 39)显著高于单腺涎管造影计算的辐射剂量(0.14 mSv,n = 42)(P < 0.001)。

结论

诊断性下颌下腺涎管造影术通常具有治疗作用,且辐射暴露有限。正在进行前瞻性研究以更详细地评估该操作的治疗效果。

证据级别

4级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd6/12369398/fdfdefebbe73/LIO2-10-e70248-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验