Konuk Suat, Özel Alp, Özsarı Emine, Nasırcılar Aşkın
Department of Chest Diseases, Faculty of Medicine, Bolu Abant Izzet Baysal University, Turkey.
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bolu Abant Izzet Baysal University, Turkey.
J Int Med Res. 2025 Aug;53(8):3000605251368253. doi: 10.1177/03000605251368253. Epub 2025 Aug 25.
ObjectiveThis study investigated the prevalence of fibromyalgia syndrome in individuals with chronic obstructive pulmonary disease and examined its association with the demographic and clinical variables of these individuals.MethodsA cross-sectional design was used to compare 100 individuals with chronic obstructive pulmonary disease with 100 age- and sex-matched healthy controls. Fibromyalgia syndrome was diagnosed based on the 2016 American College of Rheumatology criteria.ResultsThe prevalence of fibromyalgia syndrome was significantly greater in individuals with chronic obstructive pulmonary disease (16%) than in healthy controls (3%) (p = 0.048). In the chronic obstructive pulmonary disease group, female patients exhibited a markedly higher prevalence of fibromyalgia syndrome than male patients (31.6% vs. 6.4%, p = 0.035). No significant associations were found between the presence of fibromyalgia syndrome and patient age, disease duration, or chronic obstructive pulmonary disease severity. Patients with both chronic obstructive pulmonary disease and fibromyalgia syndrome frequently reported increased fatigue, sleep disturbances, and depressive symptoms.ConclusionsThese findings underscore the clinical relevance of fibromyalgia syndrome as a comorbidity in chronic obstructive pulmonary disease, particularly in women, and highlight the need for its routine screening in respiratory care. Incorporating fibromyalgia syndrome assessment may improve symptom management and support a more holistic approach to rehabilitation and disease management in chronic obstructive pulmonary disease patients.
目的
本研究调查了慢性阻塞性肺疾病患者中纤维肌痛综合征的患病率，并探讨了其与这些患者的人口统计学和临床变量之间的关联。
方法
采用横断面设计，将100例慢性阻塞性肺疾病患者与100例年龄和性别匹配的健康对照进行比较。根据2016年美国风湿病学会标准诊断纤维肌痛综合征。
结果
慢性阻塞性肺疾病患者中纤维肌痛综合征的患病率（16%）显著高于健康对照（3%）（p = 0.048）。在慢性阻塞性肺疾病组中，女性患者纤维肌痛综合征的患病率明显高于男性患者（31.6%对6.4%，p = 0.035）。未发现纤维肌痛综合征的存在与患者年龄、病程或慢性阻塞性肺疾病严重程度之间存在显著关联。同时患有慢性阻塞性肺疾病和纤维肌痛综合征的患者经常报告疲劳增加、睡眠障碍和抑郁症状。
结论
这些发现强调了纤维肌痛综合征作为慢性阻塞性肺疾病合并症的临床相关性，尤其是在女性中，并突出了在呼吸护理中对其进行常规筛查的必要性。纳入纤维肌痛综合征评估可能会改善症状管理，并支持对慢性阻塞性肺疾病患者采取更全面的康复和疾病管理方法。
