Fischer S, Hanefeld M, Weck M, Beckert H, Julius U, Eichhorn D, Rothe G, Leonhardt W, Graeser K, Haller H
Dtsch Z Verdau Stoffwechselkr. 1985;45(5):228-35.
We investigated the influence of a PSMF on body weight, body composition, blood lipids, physical working capacity, and nitrogen balance in obese HLP patients. During 4 weeks, 12 patients were treated by PSMF (approximately 340 kcal/d) under health resort conditions. At the same time, they daily exercised on a bicycle with an intensity of 80% of their physical working capacity estimated by an exercise load. The therapeutic regimen induced a significant weight loss (10.1 kg in the mean). Evidently, the patients diminished their body fat only as could be shown by estimations of total body water. Triglycerides, total cholesterol, and LDL-cholesterol also decreased significantly, while HDL-cholesterol remained unchanged. In spite of the weight reduction, the physical working capacity significantly increased from 57.8 to 93.2 kgm. Measurements of total nitrogen excretion with urine gave evidence of the protein saving effect of the therapy. Thus, PSMF--representing an effective therapeutic procedure--can be recommended to be used in obese HLP patients, proceeded that contraindications have been taken into consideration carefully.
我们研究了极低热量蛋白质膳食（PSMF）对肥胖型高脂蛋白血症（HLP）患者体重、身体成分、血脂、体力工作能力和氮平衡的影响。在4周时间里，12名患者在疗养条件下接受了PSMF治疗（约340千卡/天）。同时，他们每天以相当于运动负荷估算的体力工作能力80%的强度进行骑自行车锻炼。该治疗方案导致体重显著下降（平均减重10.1千克）。显然，通过总体水估算表明患者仅减少了身体脂肪。甘油三酯、总胆固醇和低密度脂蛋白胆固醇也显著降低，而高密度脂蛋白胆固醇保持不变。尽管体重减轻，但体力工作能力从57.8千克米显著提高到93.2千克米。尿中总氮排泄量的测量证明了该疗法的蛋白质节省效果。因此，PSMF作为一种有效的治疗方法，在仔细考虑禁忌症后，可推荐用于肥胖型HLP患者。
