• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

青少年抑郁症非指导性认知行为疗法的全国性实施:SPARX观察性研究

Nationwide Implementation of Unguided Cognitive Behavioral Therapy for Adolescent Depression: Observational Study of SPARX.

作者信息

Fleming Terry, Lucassen Mathijs, Frampton Chris, Parag Varsha, Bullen Chris, Merry Sally, Shepherd Matthew, Stasiak Karolina

机构信息

Te Kura Tātai Hauora School of Health, Victoria University of Wellington, PO Box 600, Wellington, 6140, New Zealand, 64 7961680776, 64 800 04 04 04.

Department of Epidemiology and Biostatistics, The University of Auckland, Auckland, New Zealand.

出版信息

J Med Internet Res. 2025 Aug 25;27:e66047. doi: 10.2196/66047.

DOI:10.2196/66047
PMID:40855679
Abstract

BACKGROUND

Internet-based cognitive behavioral therapy (iCBT) interventions are effective in clinical trials; however, iCBT implementation data are seldom reported.

OBJECTIVE

The objective of this study is to evaluate uptake, adherence, and changes in symptoms of depression for 12- to 19-year-olds using an unguided pure self-help iCBT intervention (SPARX; Smart, Positive, Active, Realistic, X-factor thoughts) during the first 7 years of it being publicly available without referral in Aotearoa New Zealand.

METHODS

SPARX is a 7-module, self-help intervention designed for adolescents with mild to moderate depression. It is freely accessible to anyone with a New Zealand Internet Protocol address, without the need for a referral, and is delivered in an unguided "serious game" format. The New Zealand implementation of SPARX includes 1 symptom measure-the Patient Health Questionnaire adapted for Adolescents (PHQ-A)-which is embedded at the start of modules 1, 4, and 7. We report on uptake, the number of modules completed, and changes in depressive symptoms as measured by the PHQ-A.

RESULTS

In total, 21,320 adolescents aged 12 to 19 years (approximately 2% of New Zealand 12- to 19-year-olds) registered to use SPARX. Of these, 63.6% (n=13,564; comprising n=8499, 62.7% female, n=4265, 31.4% male, and n=800, 5.9% another gender identity or gender not specified; n=8741, 64.4% New Zealand European, n=1941, 14.3% Māori, n=1202, 8.9% Asian, n=538, 4.0% Pacific, and n=1142, 8.4% another ethnic identity; mean age 14.9, SD 1.9 years) started SPARX. The mean PHQ-A at baseline was 13.6 (SD 7.7) with 16.1% (n=1980) reporting no or minimal symptoms, 37.4% (n=4609) reporting mild to moderate symptoms (ie, the target group) and 46.7% (n=5742) reporting moderately severe or severe symptoms. Among those who started, 51.1% (n=6927) completed module 1, 7.4% (n=997) completed at least 4 modules, and 3.1% (n=416) completed all 7 modules. The severity of symptoms reduced from baseline to modules 4 and 7. Mean PHQ-A scores for baseline, module 4, and module 7 for those who completed 2 or more assessments were 14.0 (SD 7.0), 11.8 (SD 7.9), and 10.5 (SD 8.5), respectively; mean difference for modules 1-4 was 2.2 (SD 5.7; P<.001) and for modules 1-7 was 3.6 (SD 7.0; P<.001). Corresponding effect sizes were 0.38 (modules 1-4) and 0.51 (modules 1-7).

CONCLUSIONS

SPARX reached a meaningful proportion of the adolescent population. The effect size for those who engaged with it was comparable to trial results. However, completion was low. Key challenges included logistical barriers such as slow download speeds and compatibility with some devices. Ongoing attention to rapidly evolving technologies and engagement with them are required. Real-world implementation analyses offer important insights for understanding and improving the impact of evidence-based digital tools and should be routinely reported.

摘要

背景

基于互联网的认知行为疗法(iCBT)干预措施在临床试验中是有效的;然而,iCBT实施数据很少被报告。

目的

本研究的目的是评估在新西兰奥塔哥地区,一种无引导的纯自助式iCBT干预措施(SPARX;明智、积极、主动、现实、X因素思维)在公开可用的前7年中,12至19岁青少年对其的接受程度、依从性以及抑郁症状的变化,无需转诊。

方法

SPARX是一种为轻度至中度抑郁症青少年设计的7模块自助干预措施。任何拥有新西兰互联网协议地址的人都可以免费使用,无需转诊,并且以无引导的“严肃游戏”形式提供。SPARX在新西兰的实施包括1种症状测量工具——适用于青少年的患者健康问卷(PHQ-A),该问卷嵌入在第1、4和7模块的开头。我们报告接受程度、完成的模块数量以及PHQ-A测量的抑郁症状变化。

结果

总共有21320名12至19岁的青少年(约占新西兰12至19岁青少年的2%)注册使用SPARX。其中,63.6%(n = 13564)开始使用SPARX(包括n = 8499名女性,占62.7%;n = 4265名男性,占31.4%;n = 800名其他性别认同或未指定性别的青少年,占5.9%;n = 8741名新西兰欧洲人,占64.4%;n = 1941名毛利人,占14.3%;n = 1202名亚洲人,占8.9%;n = 538名太平洋岛民,占4.0%;n = 1142名其他种族身份的青少年,占8.4%;平均年龄14.9岁,标准差1.9岁)。基线时PHQ-A的平均得分是13.6(标准差7.7),其中16.1%(n = 1980)报告无或轻微症状,37.4%(n = 4609)报告轻度至中度症状(即目标群体),46.7%(n = 5742)报告中度严重或严重症状。在开始使用的人群中,51.1%(n = 6927)完成了第1模块,7.4%(n = 997)完成了至少4个模块,3.1%(n = 416)完成了所有7个模块。症状严重程度从基线到第4和第7模块有所降低。完成2次或更多评估的人群在基线、第4模块和第7模块的PHQ-A平均得分分别为14.0(标准差7.0)、11.8(标准差7.9)和10.5(标准差8.5);第1至4模块的平均差异为2.2(标准差5.7;P <.001),第1至7模块的平均差异为3.6(标准差7.0;P <.001)。相应的效应大小分别为0.38(第1至4模块)和0.51(第1至7模块)。

结论

SPARX覆盖了相当比例的青少年人群。参与其中的人群的效应大小与试验结果相当。然而,完成率较低。主要挑战包括后勤障碍,如下载速度慢以及与某些设备的兼容性问题。需要持续关注快速发展的技术并与之接轨。实际应用分析为理解和改善循证数字工具的影响提供了重要见解,应定期报告。

相似文献

1
Nationwide Implementation of Unguided Cognitive Behavioral Therapy for Adolescent Depression: Observational Study of SPARX.青少年抑郁症非指导性认知行为疗法的全国性实施:SPARX观察性研究
J Med Internet Res. 2025 Aug 25;27:e66047. doi: 10.2196/66047.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
3
Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults.成人焦虑症的治疗师辅助互联网认知行为疗法。
Cochrane Database Syst Rev. 2015 Mar 5(3):CD011565. doi: 10.1002/14651858.CD011565.
4
Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults.治疗师支持的针对成人焦虑症的互联网认知行为疗法。
Cochrane Database Syst Rev. 2016 Mar 12;3(3):CD011565. doi: 10.1002/14651858.CD011565.pub2.
5
Culturally Adapted Guided Internet-Based Cognitive Behavioral Therapy for Hong Kong People With Depressive Symptoms: Randomized Controlled Trial.针对有抑郁症状的香港人群的文化适应性网络引导认知行为疗法:随机对照试验。
J Med Internet Res. 2025 Feb 25;27:e64303. doi: 10.2196/64303.
6
Precision computerised cognitive behavioural therapy (cCBT) intervention for adolescents with depression (SPARX-UK): protocol for the process evaluation of a pilot randomised controlled feasibility trial.针对青少年抑郁症的精准计算机化认知行为疗法(cCBT)干预(英国SPARX):一项试点随机对照可行性试验的过程评估方案
BMJ Open. 2025 Aug 5;15(8):e092483. doi: 10.1136/bmjopen-2024-092483.
7
Psychological therapies for treatment-resistant depression in adults.成人难治性抑郁症的心理治疗
Cochrane Database Syst Rev. 2018 May 14;5(5):CD010558. doi: 10.1002/14651858.CD010558.pub2.
8
Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents.基于认知行为疗法(CBT)、第三代CBT和人际治疗(IPT)的干预措施,用于预防儿童和青少年的抑郁症。
Cochrane Database Syst Rev. 2016 Aug 9;2016(8):CD003380. doi: 10.1002/14651858.CD003380.pub4.
9
Race, Ethnicity, and Other Cultural Background Factors in Trials of Internet-Based Cognitive Behavioral Therapy for Depression: Systematic Review.种族、民族和其他文化背景因素在基于互联网的认知行为疗法治疗抑郁症试验中的作用:系统评价。
J Med Internet Res. 2024 Feb 1;26:e50780. doi: 10.2196/50780.
10
E-Health interventions for anxiety and depression in children and adolescents with long-term physical conditions.针对患有长期身体疾病的儿童和青少年焦虑与抑郁的电子健康干预措施。
Cochrane Database Syst Rev. 2018 Aug 15;8(8):CD012489. doi: 10.1002/14651858.CD012489.pub2.

本文引用的文献

1
"My family won't let me." Adolescent-reported barriers to accessing mental health care.“我的家人不让我去。”青少年报告的获得心理健康护理的障碍。
J Res Adolesc. 2025 Mar;35(1):e70013. doi: 10.1111/jora.70013.
2
Distinct profiles of mental health need and high need overall among New Zealand adolescents - Cluster analysis of population survey data.新西兰青少年心理健康需求和总体高需求的明显特征 - 基于人口调查数据的聚类分析。
Aust N Z J Psychiatry. 2024 Aug;58(8):678-692. doi: 10.1177/00048674241243262. Epub 2024 Apr 10.
3
The engagement problem: A review of engagement with digital mental health interventions and recommendations for a path forward.
参与度问题:关于数字心理健康干预措施参与度的综述及未来发展路径建议
Curr Treat Options Psychiatry. 2023 Sep;10(3):119-135. doi: 10.1007/s40501-023-00297-3. Epub 2023 Aug 25.
4
Reasons for non-adherence with antidepressants using the Medication Adherence Reasons Scale in five European countries and United States.在五个欧洲国家和美国,使用药物依从性原因量表评估抗抑郁药不依从的原因。
J Affect Disord. 2024 Jan 1;344:446-450. doi: 10.1016/j.jad.2023.10.010. Epub 2023 Oct 11.
5
From formative design to service-ready therapeutic: A pragmatic approach to designing digital mental health interventions across domains.从形成性设计到可用于服务的疗法:跨领域设计数字心理健康干预措施的实用方法。
Internet Interv. 2023 Sep 28;34:100677. doi: 10.1016/j.invent.2023.100677. eCollection 2023 Dec.
6
Long-Term Efficacy of Internet-Based Cognitive Behavioral Therapy Self-Help Programs for Adults With Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials.基于互联网的认知行为疗法自助项目对成年抑郁症患者的长期疗效:随机对照试验的系统评价和荟萃分析
JMIR Ment Health. 2023 Aug 22;10:e46925. doi: 10.2196/46925.
7
Human contact in internet-based interventions for depression: A pre-registered replication and meta-analysis of randomized trials.基于互联网的抑郁症干预中的人际接触:一项预注册的随机试验复制及荟萃分析。
Internet Interv. 2023 Mar 31;32:100617. doi: 10.1016/j.invent.2023.100617. eCollection 2023 Apr.
8
Effectiveness of Psychotherapy for Internalising Symptoms in Children and Adolescents When Delivered in Routine Settings: A Systematic Review and Meta-analysis.心理疗法在常规环境下治疗儿童和青少年内化症状的效果:系统评价和荟萃分析。
Clin Child Fam Psychol Rev. 2023 Sep;26(3):824-848. doi: 10.1007/s10567-023-00433-8. Epub 2023 Apr 14.
9
Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems.克服患者依从性障碍:开发创新药物传递系统的案例。
Nat Rev Drug Discov. 2023 May;22(5):387-409. doi: 10.1038/s41573-023-00670-0. Epub 2023 Mar 27.
10
The role of gamification in digital mental health.游戏化在数字心理健康中的作用。
World Psychiatry. 2023 Feb;22(1):46-47. doi: 10.1002/wps.21041.