Serenari Matteo, Ratti Francesca, Hilal Mohammed Abu, Ardito Francesco, Berardi Giammauro, Boggi Ugo, Cappelli Alberta, Cescon Matteo, Cillo Umberto, Cucchetti Alessandro, De Carlis Luciano, De Cobelli Francesco, Di Benedetto Fabrizio, Ercolani Giorgio, Ettorre Giuseppe Maria, Fedi Massimo, Ferrero Alessandro, Giuliante Felice, Grazi Gian Luca, Gringeri Enrico, Gruttadauria Salvatore, Izzo Francesco, Maestri Marcello, Magistri Paolo, Massani Marco, Mazzaferro Vincenzo, Memeo Riccardo, Mocchegiani Federico, Mosconi Cristina, Patrono Damiano, Ravaioli Matteo, Romano Fabrizio, Rompianesi Gianluca, Russolillo Nadia, Ruzzenente Andrea, Sposito Carlo, Troisi Roberto, Vennarecci Giovanni, Viganò Luca, Vivarelli Marco, Zanus Giacomo, Baptista Pedro M, Oldhafer Karl, Schadde Erik, Aldrighetti Luca, Jovine Elio
Hepato-Biliary Surgery and Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Via Albertoni 15, 40138, Bologna, Italy.
Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Updates Surg. 2025 Aug 26. doi: 10.1007/s13304-025-02364-1.
In candidates for hepatectomy, different techniques to induce liver hypertrophy and modulate the future liver remnant are available. However, their use in specific clinical scenarios is highly heterogeneous and there is no consensus about minimal safety standards needed to incorporate these strategies into routine clinical practice. The aim of this position paper was to summarize newly available evidence in the field and compare medical practice among different hepatobiliary surgical units to evaluate the transformative potential of liver hypertrophy techniques in surgical oncology. This paper sets the stage for a future structured consensus on the application of liver hypertrophy techniques before hepatectomy.
对于肝切除术的候选者，有多种诱导肝肥大和调节未来肝剩余体积的技术。然而，它们在特定临床场景中的应用高度异质，对于将这些策略纳入常规临床实践所需的最低安全标准也没有共识。本立场文件的目的是总结该领域新获得的证据，并比较不同肝胆外科单位的医疗实践，以评估肝肥大技术在外科肿瘤学中的变革潜力。本文为未来肝切除术前肝肥大技术应用的结构化共识奠定了基础。
