Martin R J, Ramsay T G, Campion D R, Hausman G J
Growth. 1985 Autumn;49(3):400-7.
Early development changes in hormone levels were investigated in strains of pigs with genetic propensities for excessive lipid deposition. Fetal serum growth hormone was lowest in the preobese pigs (Ossabaw and high backfat). Fetal serum triiodothyronine was significantly elevated in the fetal pigs from obese strains. Fetal serum cortisol was highest in the high backfat pigs. There were no statistically significant differences in fetal serum glucagon. Ossabaw (obese) sows have higher serum glucose levels during gestation than low backfat or high backfat sows. This hyperglycemia is reflected in higher serum glucose levels in 110 day old Ossabaw fetal pigs. High backfat sows have higher serum triglyceride levels that low backfat or Ossabaw sows. The Ossabaw fetal pig has lower serum triglycerides than either the high backfat or the low backfat fetuses. These studies characterize early changes in serum metabolites and hormones in pigs which have the genetic propensity for obesity. At 110 days of gestation these pigs are similar in body at content (less than 1%). It is proposed that the lower level of growth hormone in the preobese fetal pig promoted a lower rate of lean body growth and a higher rate of lipid deposition postnatally.
对具有过度脂质沉积遗传倾向的猪品系的激素水平早期发育变化进行了研究。肥胖前期猪（奥萨巴猪和高背膘猪）的胎儿血清生长激素水平最低。肥胖品系的胎猪胎儿血清三碘甲状腺原氨酸显著升高。高背膘猪的胎儿血清皮质醇水平最高。胎儿血清胰高血糖素无统计学显著差异。奥萨巴（肥胖）母猪在妊娠期的血清葡萄糖水平高于低背膘或高背膘母猪。这种高血糖反映在110日龄奥萨巴胎猪的较高血清葡萄糖水平上。高背膘母猪的血清甘油三酯水平高于低背膘或奥萨巴母猪。奥萨巴胎猪的血清甘油三酯低于高背膘或低背膘胎儿。这些研究描述了具有肥胖遗传倾向的猪血清代谢物和激素的早期变化。在妊娠110天时，这些猪的体脂含量相似（低于1%）。有人提出，肥胖前期胎猪生长激素水平较低，导致出生后瘦体生长率较低，脂质沉积率较高。
