Ali Suhaila A, El-Setouhy Maged, Albasheer Osama, Alqassim Ahmad Y, Muaddi Mohammed A, Jareebi Mohammad A, Mkeen Anwar M, Alattas Khlood Khalid M, Moheedin A Alshareef Ghadh, Koko Remas Fahad I, Masmali Ohuod Mohammed H, Mohammed A Julajil Faya, Dalak Fatimah Eissa L, Hakami Rahf Ali, Alharbi Abdullah A
Department of Family and Community Medicine, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Medicine (Baltimore). 2025 Aug 22;104(34):e43817. doi: 10.1097/MD.0000000000043817.
Speech delay can affect a child's academic performance, communication skills, and social interactions later in life. Despite its prevalence, gaps remain in understanding the risk factors associated with speech delay, particularly in diverse populations. This study aimed to identify sociodemographic, health, and environmental determinants of speech delay in children. This was an age-matched case-control study. A total of 282 responses were collected from the case group and 409 responses were received from the control group in the period from September 2022 to May 2023. Descriptive analysis was used to determine the characteristics of the cases and controls. Logistic regression analysis was employed to examine the association between speech delay and various factors, adjusting for potential confounders, such as age, sex, family history, and health conditions. Boys were significantly more likely to have speech delay than girls (odds ratio [OR], 3.05; 95% CI: 2.18-4.29, P < .001). Children with a family history of speech delay (OR: 2.38, 95% CI: 1.32-4.29, P = .004) were more than twice as likely to have speech delay. Lower educational levels of both fathers (OR: 4.21, 95% CI: 1.35-14.24, P = .015) and mothers (OR: 2.45, 95% CI: 1.27-4.77, P = .008) were significantly associated with a higher risk of speech delay. Moreover, nursery attendance and health conditions, including autism, attention deficit hyperactivity disorder (ADHD), and hearing loss, were strongly associated with speech delay (P < .05). However, family income and parental employment did not show a strong association with delayed speech. This study highlights key factors such as gender, parental education, family history, and certain health conditions (autism, ADHD, and hearing impairment) as strong and significant predictors of speech delay in children. Findings underscore the need for targeted interventions and early screenings to mitigate risks, especially for children in vulnerable groups. Future research should explore the interplay of environmental and genetic factors and refine prevention strategies.
语言发育迟缓会影响儿童日后的学业成绩、沟通能力和社交互动。尽管其很常见,但在理解与语言发育迟缓相关的风险因素方面仍存在差距,尤其是在不同人群中。本研究旨在确定儿童语言发育迟缓的社会人口学、健康和环境决定因素。这是一项年龄匹配的病例对照研究。在2022年9月至2023年5月期间,病例组共收集到282份回复,对照组收到409份回复。采用描述性分析来确定病例组和对照组的特征。采用逻辑回归分析来检验语言发育迟缓与各种因素之间的关联,并对年龄、性别、家族史和健康状况等潜在混杂因素进行调整。男孩出现语言发育迟缓的可能性显著高于女孩(优势比[OR]为3.05;95%置信区间:2.18 - 4.29,P < 0.001)。有语言发育迟缓家族史的儿童(OR:2.38,95%置信区间:1.32 - 4.29,P = 0.004)出现语言发育迟缓的可能性是无家族史儿童的两倍多。父亲(OR:4.21,95%置信区间:1.35 - 14.24,P = 0.015)和母亲(OR:2.45,95%置信区间:1.27 - 4.77,P = 0.008)的教育水平较低与语言发育迟缓风险较高显著相关。此外,上托儿所情况和健康状况,包括自闭症、注意力缺陷多动障碍(ADHD)和听力损失,与语言发育迟缓密切相关(P < 0.05)。然而,家庭收入和父母就业情况与语言发育迟缓没有很强的关联。本研究强调了性别、父母教育程度、家族史和某些健康状况(自闭症、ADHD和听力障碍)等关键因素是儿童语言发育迟缓的强有力且显著的预测因素。研究结果强调了有针对性的干预措施和早期筛查以降低风险的必要性,特别是对于弱势群体中的儿童。未来的研究应探索环境和遗传因素的相互作用,并完善预防策略。