Chen Yu-Fei, Zhao Qian, Hamulati Xieyire, Cai Liting, Qiu Xinyu, Maimaitiyiming Jiamule, Liu Fen, Li Xiao-Mei, Yang Yi-Ning
Department of Coronary Heart Disease, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Front Cardiovasc Med. 2025 Aug 11;12:1618094. doi: 10.3389/fcvm.2025.1618094. eCollection 2025.
The study explores the prevalence of hypertension and evaluates the joint association of sleep quality and physical activity (PA) levels in influencing hypertension among the Kazakh agricultural workers in Xinjiang.
In this chronic disease study conducted in Xinjiang, participants were selected from Habahe County, a predominantly Kazakh region, between October and November 2023. Restricted cubic spline (RCS) analysis and multivariate logistic regression models were used to evaluate the associations between sleep quality, PA levels, and the prevalence of hypertension.
In this study of 2,872 participants, the median age was 49 (42-57) years. Among participants, 1,253 (43.63%) were male. The study resulting in a hypertension prevalence of 54.94%. RCS regression showed a linear association between sleep quality and hypertension prevalence in participants ( overall = 0.007, nonlinear = 0.214), and the association between PA level and hypertension prevalence was also statistically significant ( overall = 0.022). As PA level increased, hypertension prevalence gradually declined but stabilized at higher level. In a multivariate regression analysis adjusting for potential confounders, poorer sleep quality was associated with an increased prevalence of hypertension (OR = 1.33, 95% CI: 1.07-1.65, = 0.011; OR = 1.38, 95% CI: 1.12-1.69, = 0.001), while the association between PA level and hypertension prevalence was not statistically significant ( > 0.05). Further analysis showed that in the moderate PA level group, good sleep quality was significantly associated with a lower prevalence of hypertension (OR = 0.71, 95% CI: 0.52-0.97, = 0.031). However, in individuals with low (<6,000 METs × min/week) and high (>12,000 METs × min/week) PA levels, the association between sleep quality and hypertension prevalence was not been observed ( > 0.05).
The current study showed that PA and sleep quality are associated with the prevalence of hypertension. Among individuals with moderate PA level, healthy sleep quality may have a protective effect against hypertension.
本研究探讨新疆哈萨克族农业劳动者高血压的患病率,并评估睡眠质量和身体活动(PA)水平对高血压影响的联合关联。
在新疆开展的这项慢性病研究中,研究对象于2023年10月至11月从以哈萨克族为主的哈巴河县选取。采用受限立方样条(RCS)分析和多因素逻辑回归模型评估睡眠质量、PA水平与高血压患病率之间的关联。
在这项纳入2872名参与者的研究中,年龄中位数为49(42 - 57)岁。参与者中,1253名(43.63%)为男性。研究得出高血压患病率为54.94%。RCS回归显示参与者的睡眠质量与高血压患病率之间存在线性关联(总体 = 0.007,非线性 = 0.214),PA水平与高血压患病率之间的关联也具有统计学意义(总体 = 0.022)。随着PA水平升高,高血压患病率逐渐下降,但在较高水平时趋于稳定。在调整潜在混杂因素的多因素回归分析中,较差的睡眠质量与高血压患病率增加相关(OR = 1.33,95%CI:1.07 - 1.65,P = 0.011;OR = 1.38,95%CI:1.12 - 1.69,P = 0.001),而PA水平与高血压患病率之间的关联无统计学意义(P > 0.05)。进一步分析表明,在中等PA水平组中,良好的睡眠质量与较低的高血压患病率显著相关(OR = 0.71,95%CI:0.52 - 0.97,P = 0.031)。然而,在低(<6000 METs×min/周)和高(>12000 METs×min/周)PA水平的个体中,未观察到睡眠质量与高血压患病率之间的关联(P > 0.05)。
当前研究表明,PA和睡眠质量与高血压患病率相关。在中等PA水平的个体中,健康的睡眠质量可能对高血压具有保护作用。