Health Examination Center, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China; Center for Cardiovascular and Cerebrovascular Epidemiology and Translational Medicine, Guoke Ningbo Life Science and Health Industry Research Institute, Ningbo, Zhejiang, China.
Health Examination Center, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China.
Arch Gerontol Geriatr. 2024 Apr;119:105314. doi: 10.1016/j.archger.2023.105314. Epub 2023 Dec 14.
The relationship between sleep duration or sleep quality and the risk of hypertension has been previously examined. However, little is known regarding the association between sleep duration and quality and the risk of developing hypertension in the older adult Chinese population.
The sleep patterns of 5683 participants without hypertension at baseline from the Chinese Longitudinal Healthy Longevity Survey were analyzed. Cox proportional hazard models were used to study the associations between sleep patterns and hypertension.
It was found that 1712 (30.12%) of the 5683 participants had an unhealthy sleep pattern. After an average follow-up of 3.31 years, 1350 of the participants had hypertension. Compared with participants with an unhealthy sleep pattern, those with a healthy sleep pattern had a 20% (hazard ratio = 0.80, 95% confidence interval = 0.67-0.94, P = = 0.008) lower risk of incident hypertension in the fully adjusted models. In addition, an approximately linear dose-response association was observed between sleep duration and the incidence of hypertension (P for non-linear =0.43). Subgroup analyses demonstrated significant interactions between age and sleep pattern concerning hypertension (P for interaction <0.05). Several sensitivity analyses were conducted, and the obtained findings were similar to the main results.
A healthy sleep pattern, comprising an adequate sleep duration and good sleep quality, can help reduce hypertension risk. Thus, a healthy sleep pattern is crucial to decreasing hypertension in older Chinese adults in a rapidly aging society.
已有研究探讨了睡眠时间或睡眠质量与高血压风险之间的关系。然而，对于中国老年人群中睡眠时间和睡眠质量与高血压发病风险之间的关系知之甚少。
本研究分析了基线时无高血压的 5683 名中国长寿纵向研究参与者的睡眠模式。采用 Cox 比例风险模型研究睡眠模式与高血压之间的关联。
研究发现，5683 名参与者中有 1712 名（30.12%）存在不健康的睡眠模式。在平均 3.31 年的随访后，有 1350 名参与者患有高血压。与存在不健康睡眠模式的参与者相比，具有健康睡眠模式的参与者发生高血压的风险降低了 20%（风险比=0.80，95%置信区间=0.67-0.94，P=0.008）。此外，睡眠时间与高血压的发生呈近似线性剂量-反应关系（非线性 P 值=0.43）。亚组分析表明，年龄和睡眠模式与高血压之间存在显著的交互作用（交互作用 P 值<0.05）。进行了几项敏感性分析，所得结果与主要结果相似。
健康的睡眠模式，包括充足的睡眠时间和良好的睡眠质量，可以帮助降低高血压风险。因此，在老龄化迅速的社会中，对于中国老年人群来说，健康的睡眠模式对于降低高血压至关重要。
