Pettersson F, Björkholm E, Näslund I
Int J Epidemiol. 1985 Dec;14(4):521-7. doi: 10.1093/ije/14.4.521.
Papanicolaou screening for cancer of the uterine cervix was introduced in Sweden in the late 1950's. Screening programmes covering the age groups 30-49 years were organized in various countries between 1965 and 1973. The approximate number of smears rose from 100 000 in 1960 to one million in 1970, in a female population of four million. Almost 60 000 cases of in situ carcinoma and 17 100 invasive carcinomas of the uterine cervix were registered in Sweden between 1958 and 1980. The age-standardized incidence of invasive carcinoma fell in this period by about 40%. Within the screened cohorts and age groups, the incidence was reduced by two-thirds and there was a parallel fall in mortality from the disease. At least part of these reductions seemed to be explained by the intensity of screening.
巴氏涂片筛查子宫颈癌于20世纪50年代末在瑞典被引入。1965年至1973年间,各国组织了针对30至49岁年龄组的筛查项目。在400万女性人口中,涂片检查的数量从1960年的约10万例增加到1970年的100万例。1958年至1980年间,瑞典登记了近6万例子宫颈原位癌和17100例浸润性子宫颈癌。在此期间,浸润性癌的年龄标准化发病率下降了约40%。在接受筛查的队列和年龄组中,发病率降低了三分之二,该疾病的死亡率也相应下降。这些降低至少部分似乎可以用筛查强度来解释。