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居家医院管理急性重症溃疡性结肠炎的可行性:一项回顾性病例系列研究

Feasibility of a Hospital at Home for Management of Acute Severe Ulcerative Colitis: A Retrospective Case Series.

作者信息

Goyal Anupama A, Berinstein Jeffrey A, Shrinivas Bishu, Higgins Peter D R, Taylor Stephanie

机构信息

Division of Hospital Medicine, University of Michigan, Ann Arbor, Michigan, USA.

Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

Case Rep Gastrointest Med. 2025 Aug 18;2025:4355773. doi: 10.1155/crgm/4355773. eCollection 2025.

DOI:10.1155/crgm/4355773
PMID:40862275
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12377951/
Abstract

The Centers for Medicare and Medicaid's Acute Hospital Care at Home waiver in 2020 has enabled the management of acute conditions that were traditionally cared for in the hospital to transition to the home setting. To our knowledge, data regarding the management of patients with acute severe ulcerative colitis (ASUC) in hospital at home (HaH) programs has not been reported. We conducted a retrospective review of ASUC patients admitted to our HaH program from our adult hospital, who demonstrated early clinical response but required a comprehensive, closely monitored treatment environment that was provided in the patients' homes. Patients received daily evaluations by hospitalists, gastroenterologists, and registered nurses with clinical assessments, monitoring of vitals, and therapeutics (e.g., intravenous fluids, corticosteroids, etc.), alongside daily blood monitoring for worsening inflammation. Patient demographics and UC disease characteristics were extracted from electronic health records. Outcomes of interest included emergency department (ED) visit, readmission, and mortality within 30 days of index admission; hospital-acquired conditions (HACs) of interest (delirium, catheter associated infections, and falls) during HaH stay; length of stay (LOS) in traditional hospital vs. HaH phase; and need for escalation back to traditional hospital. Three eligible and consenting ASUC patients were transferred to HaH. Two were female and one male, with a mean age of 59.7 years. The mean LOS in the traditional hospital was 8.7 days (range: 4-18), and 6 days (range: 4-9) in HaH. There were no escalations from HaH back to the traditional hospital. One patient had a 30-day ED visit (33%) with readmission (33%). There were no deaths within 30 days of index admission or documented HACs during HaH stay. Our case series highlights the preliminary feasibility of HaH for the management of ASUC patients, as a promising alternative to prolonged hospital-based care, without compromising patient safety or care quality.

摘要

2020年医疗保险和医疗补助服务中心的“急性病居家医院护理”豁免政策,使得传统上在医院治疗的急性病管理得以向家庭环境过渡。据我们所知,尚未有关于在家医院(HaH)项目中急性重症溃疡性结肠炎(ASUC)患者管理的数据报告。我们对从我院成人医院转入HaH项目的ASUC患者进行了回顾性研究,这些患者表现出早期临床反应,但需要在患者家中提供全面、密切监测的治疗环境。患者接受住院医师、胃肠病学家和注册护士的每日评估,包括临床评估、生命体征监测和治疗(如静脉输液、皮质类固醇等),同时每日进行血液监测以观察炎症是否恶化。从电子健康记录中提取患者人口统计学和UC疾病特征。感兴趣的结果包括首次入院后30天内的急诊科就诊、再入院和死亡率;HaH住院期间的感兴趣的医院获得性疾病(HACs)(谵妄、导管相关感染和跌倒);传统医院与HaH阶段的住院时间(LOS);以及升级转回传统医院的需求。三名符合条件并同意的ASUC患者被转入HaH。两名女性,一名男性,平均年龄59.7岁。传统医院的平均住院时间为8.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77b/12377951/7b1dba13d26b/CRIGM2025-4355773.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77b/12377951/7b1dba13d26b/CRIGM2025-4355773.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77b/12377951/7b1dba13d26b/CRIGM2025-4355773.001.jpg

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本文引用的文献

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Understanding the Perspectives and Experiences of Patients with Acute Severe Ulcerative Colitis in the Hospital: A Qualitative Analysis.了解急性重度溃疡性结肠炎患者在医院的观点和体验:定性分析。
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In-hospital management of inflammatory bowel disease.
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Curr Opin Gastroenterol. 2023 Jul 1;39(4):274-286. doi: 10.1097/MOG.0000000000000953. Epub 2023 May 26.
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Hospitalization Experiences and Post-traumatic Stress in Inflammatory Bowel Disease: Opportunities for Change.炎症性肠病患者的住院经历与创伤后应激:变革机遇
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Ambulatory care management of 69 patients with acute severe ulcerative colitis in comparison to 695 inpatients: insights from a multicentre UK cohort study.比较 69 例急性重度溃疡性结肠炎门诊治疗与 695 例住院患者的管理:来自英国多中心队列研究的见解。
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