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新黄质:一种有前景的药用和营养类胡萝卜素。

Neoxanthin: A Promising Medicinal and Nutritional Carotenoid.

作者信息

Zhao Jiarong, Zhuang Gengjie, Zhang Jinrong

机构信息

College of Food Sciences and Engineering, Ningbo University, Ningbo 315211, China.

School of Marine Sciences, Ningbo University, Ningbo 315211, China.

出版信息

Mar Drugs. 2025 Aug 1;23(8):317. doi: 10.3390/md23080317.

DOI:10.3390/md23080317
PMID:40863634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12387748/
Abstract

Neoxanthin is a xanthophyll carotenoid with high-value nutritional functions for human health due to its anti-cancer, anti-oxidative, and anti-obesity activities. In this present work, we systematically reviewed the structure, source, and biosynthetic pathways of neoxanthin, and discussed the advantages and disadvantages of the prevailing extraction methods of neoxanthin. Meanwhile, this review described the latest research progress on the pharmacological activities of neoxanthin. Finally, we concluded with a discussion on the main challenges of neoxanthin production from microalgae, and proposed some future development prospects and potential solutions.

摘要

新黄质是一种叶黄素类胡萝卜素,因其抗癌、抗氧化和抗肥胖活性而对人体健康具有高价值的营养功能。在本研究中,我们系统地综述了新黄质的结构、来源和生物合成途径,并讨论了现行新黄质提取方法的优缺点。同时,本综述描述了新黄质药理活性的最新研究进展。最后,我们讨论了从微藻生产新黄质的主要挑战,并提出了一些未来的发展前景和潜在解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/6106d31c5a02/marinedrugs-23-00317-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/f231c3ee2eaa/marinedrugs-23-00317-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/ca04266cc73a/marinedrugs-23-00317-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/0789dec72236/marinedrugs-23-00317-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/6106d31c5a02/marinedrugs-23-00317-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/f231c3ee2eaa/marinedrugs-23-00317-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/ca04266cc73a/marinedrugs-23-00317-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/0789dec72236/marinedrugs-23-00317-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1416/12387748/6106d31c5a02/marinedrugs-23-00317-g004.jpg

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本文引用的文献

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Optimization of accelerated solvent extraction of zeaxanthin from orange paprika using response surface methodology and an artificial neural network coupled with a genetic algorithm.使用响应面法以及结合遗传算法的人工神经网络对从甜椒中加速溶剂萃取玉米黄质进行优化。
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Antioxidant Enzymes in Cancer Cells: Their Role in Photodynamic Therapy Resistance and Potential as Targets for Improved Treatment Outcomes.
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Microalgae, Seaweeds and Aquatic Bacteria, Archaea, and Yeasts: Sources of Carotenoids with Potential Antioxidant and Anti-Inflammatory Health-Promoting Actions in the Sustainability Era.微藻、海藻和水生细菌、古菌和酵母:在可持续发展时代具有抗氧化和抗炎保健作用的类胡萝卜素的来源。
Mar Drugs. 2023 Jun 1;21(6):340. doi: 10.3390/md21060340.
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Advanced methods of algal pigments extraction: A review.藻类色素提取的先进方法:综述。
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