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获得性中枢神经系统损伤后肩部疾病的诊断及多模式管理途径,包括肉毒杆菌神经毒素治疗

Pathways for Diagnosis and Multimodal Management, Including Botulinum Neurotoxin Therapy, in Shoulder Conditions Following Acquired Central Nervous System Lesions.

作者信息

Biering-Sørensen Bo, Cordero-García Carlos, Boulias Chris, Hoad Damon, Bensmail Djamel, Molteni Franco, Genêt François, Wissel Jörg, Jacinto Jorge, Marque Philippe, Berweck Steffen

机构信息

Rigshospitalet, Neurological Department, Movement Disorder and Pain Research Center, 2600 Copenhagen, Denmark.

Hospital Universitario Juan Ramón Jiménez, 21005 Huelva, Spain.

出版信息

Toxins (Basel). 2025 Jul 31;17(8):385. doi: 10.3390/toxins17080385.

Abstract

There is limited published guidance available to help less experienced practitioners assess and manage shoulder conditions, including spasticity, after acquired central nervous system (CNS) lesions. To address this gap, 11 spasticity and dystonia experts convened in a 2023 meeting to build on existing guidance, provide consensus on best treatment practice, and develop expert recommendations to guide the diagnosis and treatment of complications of shoulder conditions following CNS lesions. Presentations by each expert on diagnosis and management were followed by discussion; consensus on assessment and treatment practices was identified and recommendations developed. The expert panel recommended an assessment approach structured using the following components: patient history, including interpretation of reported symptoms; observation of postures and pain responses; clinical examination with targeted tests for specific signs; diagnostic tests; and assessment of upper limb impairment, activity limitations, and participation restrictions. This assessment process and the recommended measures recognize the importance of identifying shoulder involvement in upper limb spasticity as part of the diagnostic process in shoulder conditions following CNS lesions. These recommendations provide a practical approach to diagnosis and treatment for clinicians who are less experienced in evaluating and treating such conditions, simplifying otherwise complicated clinical scenarios.

摘要

对于经验不足的从业者而言,在评估和管理获得性中枢神经系统(CNS)损伤后的肩部疾病(包括痉挛)方面,公开可用的指导有限。为了填补这一空白,11位痉挛和肌张力障碍专家在2023年的一次会议上齐聚,以现有指导为基础,就最佳治疗实践达成共识,并制定专家建议,以指导中枢神经系统损伤后肩部疾病并发症的诊断和治疗。每位专家就诊断和管理进行陈述后展开讨论;确定了评估和治疗实践的共识并制定了建议。专家小组推荐了一种结构化的评估方法,其组成部分如下:患者病史,包括对所报告症状的解读;姿势和疼痛反应的观察;针对特定体征进行有针对性检查的临床检查;诊断测试;以及上肢损伤、活动受限和参与限制的评估。这一评估过程和推荐措施认识到,在中枢神经系统损伤后肩部疾病的诊断过程中,识别上肢痉挛中的肩部受累情况具有重要意义。这些建议为在评估和治疗此类疾病方面经验不足的临床医生提供了一种实用的诊断和治疗方法,简化了原本复杂的临床情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4fa/12390038/07ac5f21f844/toxins-17-00385-g001.jpg

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