比较二维椭球体模型变体在估计犬三维超声心动图右心室容积中的应用
Comparing Two-Dimensional Ellipsoid Model Variants in Estimating Three-Dimensional Echocardiographic Right Ventricular Volume in Dogs.
作者信息
Ciardullo Robert, Tagg Brittany E, Nesta Elisabeth, Mintz Shana B, Pariaut Romain, Hsue Weihow
机构信息
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
出版信息
J Vet Intern Med. 2025 Sep-Oct;39(5):e70232. doi: 10.1111/jvim.70232.
BACKGROUND
Determining right ventricular (RV) volume typically requires three-dimensional imaging due to its complex shape. The ellipsoid model offers a two-dimensional alternative, employing area- or linear-based formulas with further variations depending on the echocardiographic views used for measurements.
HYPOTHESIS/OBJECTIVES: To identify which ellipsoid model variant best agrees with real-time three-dimensional echocardiography (RT3D) as a reference standard and to assess within-day reproducibility.
ANIMALS
Sixty-seven client-owned dogs (23 normal, 44 with right-sided heart diseases) underwent echocardiograms, with 20 normal dogs receiving a repeat examination.
METHODS
Prospective method comparison study. Body weight-indexed end-diastolic (iEDV) and end-systolic volumes (iESV) were calculated across eight ellipsoid model variants. Agreement was assessed using concordance correlation coefficients (r) and Bland-Altman analysis, while within-day reproducibility was evaluated using intraclass correlation coefficients (ICC) and reproducibility coefficients.
RESULTS
The area- and linear-based variants using RV parameters from the left apical four-chamber view and perpendicular diameter from the right parasternal short-axis view (AEM and LEM, respectively) were the only methods to achieve moderate agreement with RT3D (r > 0.90). The AEM showed no significant systematic bias for iEDV (median of the differences [95% confidence interval]: 0.09 [0.00-0.13]), while LEM exhibited no significant systematic bias for iEDV (0.03 [-0.02-0.08]) and iESV (0.04 [-0.01-0.12]), though biases increased at larger volumes. Both methods demonstrated good reproducibility (ICC > 0.75), with iESV reproducibility significantly greater than that of methods using RV parameters from the right parasternal long-axis four-chamber view.
CONCLUSIONS AND CLINICAL IMPORTANCE
The AEM and LEM offer practical RV volume estimates.
背景
由于右心室（RV）形状复杂，通常需要三维成像来确定其容积。椭球模型提供了一种二维替代方法，采用基于面积或线性的公式，根据用于测量的超声心动图视图还有进一步的变化。
假设/目标：确定哪种椭球模型变体与作为参考标准的实时三维超声心动图（RT3D）最一致，并评估日内重复性。
动物
67只客户拥有的犬（23只正常，44只患有右侧心脏病）接受了超声心动图检查，其中20只正常犬接受了重复检查。
方法
前瞻性方法比较研究。计算了八种椭球模型变体的体重指数化舒张末期容积（iEDV）和收缩末期容积（iESV）。使用一致性相关系数（r）和布兰德-奥特曼分析评估一致性，使用组内相关系数（ICC）和重复性系数评估日内重复性。
结果
使用来自左心尖四腔视图的RV参数和右胸骨旁短轴视图的垂直直径的基于面积和线性的变体（分别为AEM和LEM）是与RT3D达到中度一致性（r>0.90）的唯一方法。AEM对iEDV没有显著的系统偏差（差异中位数[95%置信区间]：0.09[0.00 - 0.13]），而LEM对iEDV（0.03[-0.02 - 0.08]）和iESV（0.04[-0.01 - 0.12]）没有显著的系统偏差，尽管在较大容积时偏差会增加。两种方法都显示出良好的重复性（ICC>0.75），iESV的重复性显著高于使用右胸骨旁长轴四腔视图的RV参数的方法。
结论及临床意义
AEM和LEM提供了实用的RV容积估计值。
Zotero 插件