Calcaterra Susan L, Lockhart Steven, Natvig Crystal, Mikulich-Gilbertson Susan K
Department of Medicine, Division of Hospital Medicine, University of Colorado, Aurora, CO, USA.
Department of Medicine, Division of General Internal Medicine, Adult and Child Center for Health Outcomes Research and Delivery Service, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.
J Gen Intern Med. 2025 Aug 27. doi: 10.1007/s11606-025-09728-8.
Opioid-related hospitalizations are highly prevalent. Hospital-based clinicians are well positioned to initiate medications for opioid use disorder (MOUD) among hospitalized adults with OUD.
Measure the perceived impact of a multi-site and multi-faceted OUD intervention to expand provision of hospital-based OUD treatment, including MOUD.
DESIGN, PARTICIPANTS, AND SETTING: Compared pre- and post-OUD intervention survey results of hospital-based clinicians practicing across 12 hospitals following implementation of an OUD intervention.
Survey questions were grouped into six domains: evidence to treat OUD; hospital processes to screen for unhealthy substance use and refer to post-discharge OUD treatment; MOUD initiation; readiness to initiate MOUD; current practices to initiate MOUD; and leadership prioritization of OUD treatment. We calculated mean summary scores across domains and measured changes across pre- and post-OUD intervention surveys. We analyzed open-ended survey questions using a team-based content analysis to identify and quantify key concepts.
Of the 213 post-OUD intervention survey respondents (61% response rate), 110 (52%) also completed the pre-survey. Compared to the pre-survey, in the post-survey, more respondents reported believing that the evidence to treat OUD was valid (p < 0.001), reported higher satisfaction with hospital processes to screen and refer to OUD treatment (p < 0.001), reported fewer concerns regarding MOUD initiation (buprenorphine: p < 0.001; methadone: p < 0.001), reported that leadership prioritized OUD treatment (p < 0.001), and reported higher readiness to initiate MOUD (buprenorphine: p < 0.001; methadone: p < 0.001). Fewer respondents reported barriers to initiate buprenorphine (p = 0.002) or methadone (p < 0.001) in the hospital. Emergent key concepts from open-ended questions included a need for ongoing education and training to treat OUD and a need for access to addiction specialists (n = 50%; n = 28% of write-in responses, respectively).
Interventions to facilitate in-hospital OUD treatment should address local barriers to providing this care, including ensuring access to addiction specialists and providing routine and accessible education to hospital-based clinicians.
与阿片类药物相关的住院情况非常普遍。医院临床医生在为患有阿片类药物使用障碍(OUD)的住院成年人启动阿片类药物使用障碍药物治疗(MOUD)方面具有良好的条件。
衡量一项多地点、多方面的OUD干预措施对扩大基于医院的OUD治疗(包括MOUD)的提供所产生的感知影响。
设计、参与者和环境:比较了在实施OUD干预措施后,12家医院的医院临床医生在OUD干预前后的调查结果。
调查问题分为六个领域:治疗OUD的证据;筛查不健康物质使用并转介出院后OUD治疗的医院流程;启动MOUD;启动MOUD的意愿;启动MOUD的当前做法;以及OUD治疗的领导优先级。我们计算了各领域的平均总结分数,并测量了OUD干预前后调查的变化。我们使用基于团队的内容分析方法分析开放式调查问题,以识别和量化关键概念。
在213名OUD干预后调查的受访者中(回复率为61%),110人(52%)也完成了预调查。与预调查相比,在调查后,更多受访者表示认为治疗OUD的证据是有效的(p<0.001),对筛查和转介OUD治疗的医院流程满意度更高(p<0.001),对启动MOUD的担忧更少(丁丙诺啡:p<0.001;美沙酮:p<0.00),表示领导将OUD治疗列为优先事项(p<0.001),并且启动MOUD的意愿更高(丁丙诺啡:p<0.001;美沙酮:p<0.001)。在医院中,报告启动丁丙诺啡(p = 0.002)或美沙酮(p<0.001)存在障碍的受访者较少。开放式问题中出现的关键概念包括需要持续的教育和培训来治疗OUD,以及需要获得成瘾专家的帮助(分别占50%;书面回复的28%)。
促进医院内OUD治疗的干预措施应解决提供此类护理的当地障碍,包括确保获得成瘾专家以及为医院临床医生提供常规且易于获得的教育。