Muircroft Wendy, Welsh Fraser
Department of Palliative Care, Waikato Hospital, Hamilton 3240, New Zealand.
Department of Surgery, Waikato Hospital, Hamilton 3240, New Zealand.
Cancers (Basel). 2025 Aug 8;17(16):2602. doi: 10.3390/cancers17162602.
: There is evidence that pancreatic cancer arises from different pre-malignant conditions, which can take decades to transform to invasive cancers. Some individuals can benefit from surveillance and early access to surgery. Patients that have disease that is detected whilst it is resectable may have the disease cured by total or partial pancreatectomy. It is already known that pancreatic cancer, whether advanced or localised, causes impairment in quality of life, and survivors of surgery can have quality of life impaired by recognised and predictable pancreatic deficiencies. : A literature review of key themes affecting quality of life in pancreatic cancer are presented here. : The biological features of the precursors of pancreatic cancer are described, with the rationale for surveillance and effects of surgical management in different conditions. : Surgery for pancreatic cancer carries the potential for high impact on quality of life after survivorship after initial surgical intervention. Identification of issues that affect patients are discussed with the aim of improving the quality of care for patients.
有证据表明胰腺癌起源于不同的癌前病变,这些病变可能需要数十年才能转变为浸润性癌症。一些个体可从监测和早期手术中获益。疾病在可切除时被检测出的患者,其疾病可能通过全胰或部分胰腺切除术治愈。已知胰腺癌无论处于晚期还是局部阶段,都会导致生活质量受损,手术幸存者的生活质量可能会因公认且可预测的胰腺功能缺陷而受损。:本文对影响胰腺癌患者生活质量的关键主题进行了文献综述。:描述了胰腺癌前体的生物学特征,以及不同情况下监测的基本原理和手术治疗的效果。:胰腺癌手术在初次手术干预后的生存期对生活质量可能产生重大影响。讨论了影响患者的问题,旨在提高对患者的护理质量。