Lorca Marcos, Vega-Muñoz Alejandro, Acosta Alison, Cabezas David, Díaz Katy, Mella Jaime, Sabadini Gianfranco, Salazar-Sepúlveda Guido, Contreras-Barraza Nicolás, Mellado Marco
Facultad de Ciencias de la Vida, Carrera de Química y Farmacia, Universidad Viña del Mar, Viña del Mar 2520000, Chile.
Facultad de Medicina y Ciencias de la Salud, Universidad Central de Chile, Santiago 8330507, Chile.
Antioxidants (Basel). 2025 Aug 11;14(8):985. doi: 10.3390/antiox14080985.
Since 2000, antioxidant research in Chile has shown steady growth, from the chemical sciences to their application in biomedical sciences, functional foods, reproduction, and environmental studies. This study presents a bibliometric analysis of Chilean scientific output in the field of antioxidants from 2000 to 2024, organized into five-year intervals. A total of 3190 research articles indexed in the Web of Science (WoS) database were analyzed. Bibliometric indicators-including Price's, Bradford's, and Zipf's laws-were applied to assess literature growth, authorship concentration, journal dispersion, and keyword evolution. Key findings include (i) high productivity from institutions such as the Universidad de Chile, Pontificia Universidad Católica de Chile, Universidad de Santiago de Chile, and Universidad de Concepción; (ii) the identification of leading authors such as Dr. Antonio Vega-Gálvez, Dr. Guillermo Schmeda-Hirschman, and Dr. Mario J. Simirgiotis; and (iii) the consolidation of three main research areas: biomedical applications (e.g., cancer, cardiovascular, and neurodegenerative diseases), food science and technology (e.g., antioxidant properties, and agro-industrial waste revalorization), and ethnopharmacology (e.g., native plant use). This study made it possible to map the state of the art of antioxidant research in Chile and identify key players and research lines, consolidating a comprehensive vision of scientific development in this field.
自2000年以来,智利的抗氧化剂研究呈现出稳步增长的态势,研究范围从化学科学扩展到其在生物医学科学、功能食品、生殖以及环境研究中的应用。本研究对2000年至2024年期间智利抗氧化剂领域的科研产出进行了文献计量分析,分析以五年为间隔进行组织。共分析了Web of Science(WoS)数据库中索引的3190篇研究文章。应用了包括普赖斯定律、布拉德福定律和齐普夫定律在内的文献计量指标来评估文献增长、作者集中度、期刊分布以及关键词演变。主要发现包括:(i)智利大学、智利天主教大学、智利圣地亚哥大学和康塞普西翁大学等机构的高产出;(ii)识别出了安东尼奥·维加 - 加尔韦斯博士、吉列尔莫·施梅达 - 赫希曼博士和马里奥·J·西米吉奥蒂斯博士等主要作者;(iii)三个主要研究领域的巩固:生物医学应用(如癌症、心血管疾病和神经退行性疾病)、食品科学与技术(如抗氧化特性以及农业工业废料的再利用)和民族药理学(如本土植物的使用)。这项研究使得描绘智利抗氧化剂研究的现状以及识别关键参与者和研究方向成为可能,巩固了对该领域科学发展的全面认识。