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与临床及《自闭症诊断观察量表第二版》(ADOS-2)结果相比,《诊断自闭症谱系访谈量表第二版》(DASI-2)的可接受性及初步验证

Acceptability and Pilot Validation of the Diagnostic Autism Spectrum Interview (DASI-2) Compared with Clinical and ADOS-2 Outcomes.

作者信息

Young Susan Jane, Kollárovics Nóra, Farkas Bernadett Frida, Torzsa Tímea, Cseh Rebecca, Ferenczi-Dallos Gyöngyvér, Balázs Judit

机构信息

Independent Practice, Psychology Services Ltd., London, CR9 7AE, UK.

Department of Psychology, University of Reykjavik, Menntavegur 1, 110 Reykjavik, Iceland.

出版信息

Children (Basel). 2025 Aug 4;12(8):1025. doi: 10.3390/children12081025.

Abstract

BACKGROUND/OBJECTIVES: There is a growing need for autism spectrum disorder (ASD) assessment tools that are diagnostically aligned, clinically usable, and accessible across diverse service contexts. The Diagnostic Autism Spectrum Interview-Version 2 (DASI-2) is a freely available, semi-structured clinical interview mapped directly to DSM-5 and ICD-11 criteria. This pilot study aimed to adapt DASI-2 into Hungarian and explore the (1) acceptability of DASI-2 administration, (2) agreement with prior clinical ASD diagnoses, and (3) relationship between DASI-2 observational ratings and ADOS-2 classifications.

METHODS

Following a multistep translation procedure, DASI-2 was administered to seven children previously assessed for ASD in a multidisciplinary Hungarian clinical setting. The assessment included a parent interview, direct assessment with the child or young person, and completion of the DASI observational record (OR1-OR4). DASI diagnostic outcomes were compared with prior clinical decisions, and OR scores were analyzed in relation to ADOS-2 classifications.

RESULTS

All participants completed the DASI-2 interview in full. Agreement with prior clinical diagnosis was found in six of seven cases (κ = 0.70, indicating substantial agreement). When exploring the one non-aligned case, the divergence in diagnostic outcome was due to broader contextual information considered by the initial clinical team which influenced clinical opinion. The five participants diagnosed with ASD showed substantially higher DASI observational scores (mean = 15.26) than the two who were not diagnosed (mean = 1.57), mirroring ADOS-2 severity classifications.

CONCLUSIONS

These findings support the acceptability and preliminary validity of DASI-2. Its inclusive structured observational record may provide a practical complement to resource-intensive tools such as the ADOS-2; however, further validation in larger and more diverse samples is needed.

摘要

背景/目的:对于自闭症谱系障碍(ASD)评估工具的需求日益增长,这些工具需要在诊断上保持一致、临床可用且能在不同服务环境中使用。《诊断性自闭症谱系访谈 - 第2版》(DASI - 2)是一种免费提供的半结构化临床访谈,直接与《精神疾病诊断与统计手册》第5版(DSM - 5)和《国际疾病分类》第11版(ICD - 11)标准相对应。这项试点研究旨在将DASI - 2改编为匈牙利语版本,并探讨(1)DASI - 2施测的可接受性,(2)与先前临床ASD诊断的一致性,以及(3)DASI - 2观察评分与《自闭症诊断观察量表第2版》(ADOS - 2)分类之间的关系。

方法

经过多步骤翻译程序后,在匈牙利多学科临床环境中,对7名先前已接受ASD评估的儿童进行了DASI - 2施测。评估包括家长访谈、对儿童或青少年的直接评估以及完成DASI观察记录(OR1 - OR4)。将DASI诊断结果与先前的临床诊断进行比较,并分析OR分数与ADOS - 2分类的关系。

结果

所有参与者都完整地完成了DASI - 2访谈。在7个案例中有6个案例与先前临床诊断结果一致(κ = 0.70,表明高度一致)。在探究1个不一致的案例时,诊断结果的差异是由于最初的临床团队考虑了更广泛的背景信息,这影响了临床判断。5名被诊断为ASD的参与者的DASI观察评分(平均 = 15.26)显著高于2名未被诊断者(平均 = 1.57),这与ADOS - 2的严重程度分类相符。

结论

这些发现支持了DASI - 2的可接受性和初步有效性。其包含性的结构化观察记录可能为诸如ADOS - 2等资源密集型工具提供实际补充;然而,需要在更大且更多样化的样本中进行进一步验证。

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