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衰老过程中社会经济因素与环境因素的交叉:一项叙述性综述的见解

The Intersection of Socioeconomic and Environmental Factors in Aging: Insights from a Narrative Review.

作者信息

Vereecke Shelby, Bennett Kalia, Schrempft Stephanie, Kobor Michael, Brauer Michael, Stringhini Silvia

机构信息

School of Population and Public Health, the University of British Columbia, Vancouver, BC V5T 1Z4, Canada.

Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, CH-1211 Genève 4 Geneva, Switzerland.

出版信息

Int J Environ Res Public Health. 2025 Aug 8;22(8):1241. doi: 10.3390/ijerph22081241.

Abstract

(1) Background: Socioeconomic conditions and environmental exposures are well-established determinants of health and aging, yet the pathways through which they influence the aging process remain insufficiently understood. Clarifying these mechanisms is critical for developing effective, equity-focused public health interventions to support healthy aging; (2) Methods: We conducted a narrative review examining the relationships between socioeconomic conditions, environmental exposures, and aging-related health outcomes. While the scope was intentionally broad to capture diverse exposures and outcomes, we applied a systematic search strategy to identify relevant peer-reviewed studies; (3) Results: The search populated over 4000 articles; 33 relevant papers were selected. The evidence suggests that environmental exposures may mediate or modify the effects of socioeconomic disadvantage on aging. Conversely, socioeconomic conditions can alter the association between environmental factors and aging outcomes. Disadvantaged populations consistently face higher environmental burdens and exhibit poorer aging outcomes, including accelerated biological aging and increased risk of age-related disease; (4) Conclusions: The complex interplay between social and environmental factors contributes to disparities in aging. Our integrative approach highlights the need for more intersectional, longitudinal research to inform interventions that address the social and environmental determinants of healthy aging.

摘要

(1)背景:社会经济状况和环境暴露是健康与衰老的既定决定因素,但它们影响衰老过程的途径仍未得到充分理解。阐明这些机制对于制定有效的、以公平为重点的公共卫生干预措施以支持健康衰老至关重要;(2)方法:我们进行了一项叙述性综述,研究社会经济状况、环境暴露与衰老相关健康结果之间的关系。虽然范围有意广泛以涵盖各种暴露和结果,但我们应用了系统的搜索策略来识别相关的同行评审研究;(3)结果:搜索产生了4000多篇文章;选择了33篇相关论文。证据表明,环境暴露可能介导或改变社会经济劣势对衰老的影响。相反,社会经济状况可以改变环境因素与衰老结果之间的关联。弱势群体始终面临更高的环境负担,并且衰老结果更差,包括生物衰老加速和患年龄相关疾病的风险增加;(4)结论:社会和环境因素之间的复杂相互作用导致了衰老方面的差异。我们的综合方法强调需要更多的交叉性纵向研究,以为解决健康衰老的社会和环境决定因素的干预措施提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c08/12386621/ed651eb5eb10/ijerph-22-01241-g001.jpg

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