Maher E R, Smith E M, Lees A J
J Neurol Neurosurg Psychiatry. 1985 Dec;48(12):1234-9. doi: 10.1136/jnnp.48.12.1234.
Clinical examination of 33 consecutive newly diagnosed cases of Steele-Richardson-Olszewski syndrome revealed evidence of cognitive impairment in 20. Eighteen of the 27 right handed patients who underwent neuropsychological assessment had intellectual impairment (mild in nine and marked in nine patients). The pattern of abnormalities was similar to but more severe than those previously reported in Parkinson's disease, with particular difficulties in carrying out tests which are believed to be sensitive to frontal lobe dysfunction.
对33例连续新诊断的斯蒂尔-理查森-奥尔谢夫斯基综合征病例进行临床检查发现,其中20例有认知障碍证据。在接受神经心理学评估的27例右利手患者中,18例有智力障碍(9例为轻度,9例为重度)。异常模式与先前帕金森病报道的相似但更严重,在进行被认为对额叶功能障碍敏感的测试时尤其困难。