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实验性肝衰竭大鼠血清吲哚乙酸水平的升高

Elevation of serum indoleacetic acid levels in rats with experimental liver failure.

作者信息

Yamada J, Sugimoto Y, Horisaka K

出版信息

J Pharmacobiodyn. 1985 Sep;8(9):780-4. doi: 10.1248/bpb1978.8.780.

Abstract

Changes in the serum levels of indoleacetic acid (IAA) of liver-injured rats induced with an injection of carbontetrachloride (CCl4) or D-galactosamine (GalN) were investigated. IAA showed a marked increase of 61.8% and 102.6% in CCl4 and GalN treated rats, respectively. The elevation of IAA was observed only in the early stages of hepatic failure.

摘要

研究了注射四氯化碳(CCl4)或D-半乳糖胺(GalN)诱导的肝损伤大鼠血清中吲哚乙酸(IAA)水平的变化。在CCl4和GalN处理的大鼠中,IAA分别显著增加了61.8%和102.6%。IAA升高仅在肝衰竭的早期阶段观察到。

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