Shalom Esther Oluwatosin, Faloye Kolade Olatubosun, Adesida Stephen Adeleke, Adewole Adetola Henry, Olatunji Oluwaseun Emmanuel, Okunribido Blessing Ibukun, Olawuni Oluwatosin Funke, Olanudun Esther Aina, Ogundele Seun Bayonle, Famuyiwa Samson Oluwaseyi
Drug Research and Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife 220101, Nigeria.
Department of Pharmacognosy, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife 220101, Nigeria.
Molecules. 2025 Aug 11;30(16):3335. doi: 10.3390/molecules30163335.
The genus has over 350 species distributed on different continents of the world. The vast majority of the species in this genus possess interesting biological activities. Also, they are good sources of flavonoids, which are known to elicit excellent pharmacological properties and are well-positioned as potential drug candidates. A literature search was performed with proper consideration of articles published and indexed in PubMed, Scopus, Springer Link, Google Scholar, ScienceDirect, SciFinder, and Medline databases between 1980 and 2023. A total of 164 flavonoids isolated from the genus were reviewed, and biological activities including antidiabetic, anti-cancer, antibacterial, cytotoxicity, antidiarrheal, antioxidant, anti-inflammatory, and anti-cataract were all reported. This study gave a comprehensive review of these flavonoids through detailed classification, structural diversity, and pharmacological activities.
该属有350多种，分布于世界不同大陆。该属的绝大多数物种具有有趣的生物活性。此外，它们是黄酮类化合物的良好来源，已知黄酮类化合物具有出色的药理特性，并且作为潜在的药物候选物具有良好的前景。在适当考虑1980年至2023年期间在PubMed、Scopus、Springer Link、Google Scholar、ScienceDirect、SciFinder和Medline数据库中发表和索引的文章的情况下进行了文献检索。共综述了从该属中分离出的164种黄酮类化合物，并报道了其生物活性，包括抗糖尿病、抗癌、抗菌、细胞毒性、止泻、抗氧化、抗炎和抗白内障等。本研究通过详细的分类、结构多样性和药理活性对这些黄酮类化合物进行了全面综述。
