Jafarnezhad Fatemeh, Nazarzadeh Ata, Bazavar Haniyeh, Keramat Shayan, Ryszkiel Ireneusz, Stanek Agata
Department of Hematology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9177948974, Iran.
Department of Hematology, Zanjan University of Medical Science, Senman 4513956184, Iran.
Nutrients. 2025 Aug 15;17(16):2656. doi: 10.3390/nu17162656.
Metabolic syndrome (MetS) is defined by a combination of metabolic abnormalities, such as central obesity, insulin resistance, hypertension, and dyslipidemia, and significantly increases the risk of cardiovascular diseases and type 2 diabetes. The high prevalence of MetS is a public health concern, necessitating rapid identification and intervention strategies to prevent this emerging epidemic. Diagnosing MetS requires the presence of three or more of these abnormalities, underscoring the need for effective management approaches. Despite a growing body of literature, limited reviews have critically evaluated the complex interplay between metabolic dysfunction, inflammation, and coagulation, particularly in the context of dietary interventions. Therefore, this article reviews the relationship between metabolic syndrome, inflammation, and thrombotic diseases, with an emphasis on their impacts on hematological health. Furthermore, this review explores the potential role of vegetarian and vegan dietary patterns in controlling these processes and improving hematological outcomes. This narrative review aims to critically evaluate current research on the inflammatory and thrombotic implications of MetS and assess the potential modulating role of vegan and plant-based diets within this context.
代谢综合征（MetS）由多种代谢异常组合而成，如中心性肥胖、胰岛素抵抗、高血压和血脂异常，它会显著增加心血管疾病和2型糖尿病的风险。代谢综合征的高患病率是一个公共卫生问题，因此需要快速识别和干预策略来预防这一新兴的流行病。诊断代谢综合征需要存在三种或更多这些异常情况，这凸显了有效管理方法的必要性。尽管有越来越多的文献，但有限的综述批判性地评估了代谢功能障碍、炎症和凝血之间的复杂相互作用，特别是在饮食干预的背景下。因此，本文综述了代谢综合征、炎症和血栓性疾病之间的关系，重点关注它们对血液健康的影响。此外，本综述探讨了素食和纯素饮食模式在控制这些过程和改善血液学结果方面的潜在作用。这篇叙述性综述旨在批判性地评估当前关于代谢综合征的炎症和血栓形成影响的研究，并评估纯素和植物性饮食在这种情况下的潜在调节作用。
