Highton J, Hessian P A, Small B, Palmer D G
J Rheumatol. 1985 Oct;12(5):854-8.
IgA rheumatoid factor (RF) was found in a significant number of the normal population. As a consequence, the presence of IgA RF was not more specific for a diagnosis of rheumatoid arthritis than IgM RF. However, further investigation of IgA RF as a prognostic indicator is important. Our results, which show an association between the presence of IgA RF and higher levels of IgM RF, suggest that careful differentiation between the predictive values of the presence of IgA RF and a high level of IgM RF will be necessary.
在大量正常人群中发现了IgA类风湿因子（RF）。因此，IgA RF的存在对于类风湿性关节炎诊断的特异性并不比IgM RF更高。然而，进一步研究IgA RF作为一种预后指标很重要。我们的结果表明IgA RF的存在与较高水平的IgM RF之间存在关联，这表明有必要仔细区分IgA RF存在和高水平IgM RF的预测价值。
