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优化艾滋病毒感染者的免疫策略:基本疫苗、疫苗接种率及依从性因素综述

Optimizing Immunization Strategies for Individuals Living with HIV: A Review of Essential Vaccines, Vaccine Coverage, and Adherence Factors.

作者信息

Würfel Lina M, Potthoff Anja, Skaletz-Rorowski Adriane, Nambiar Sandeep, Abu Rached Nessr

机构信息

Walk In Ruhr [WIR]-Centre for Sexual Health and Medicine, Große Beckstraße 12, 44787 Bochum, Germany.

Interdisciplinary Immunological Center, Centre for Sexual Health and Medicine, Department of Dermatology, Venerology und Allergology, Ruhr University Bochum, Große Beckstraße 12, 44787 Bochum, Germany.

出版信息

Vaccines (Basel). 2025 Jul 28;13(8):798. doi: 10.3390/vaccines13080798.

Abstract

Human immunodeficiency virus (HIV) infection remains a major challenge in global health. In recent years, vaccines have emerged as an important tool for the treatment and prevention of HIV-related complications. This review article addresses the evolving landscape of vaccines for people living with HIV (PLWH), evaluating current vaccination strategies for standard vaccines and travel vaccines in PLWH compared to the general population and offering a summary of the current recommended vaccines. It evaluates studies for vaccine effectiveness and safety and discusses methods to improve vaccination rates among PLWH. Systematic research was carried out using keywords. We address the current state of knowledge and highlight areas for future research and development.

摘要

人类免疫缺陷病毒(HIV)感染仍然是全球卫生领域的一项重大挑战。近年来,疫苗已成为治疗和预防HIV相关并发症的重要工具。这篇综述文章探讨了HIV感染者(PLWH)疫苗的不断变化的格局,评估了与普通人群相比PLWH中标准疫苗和旅行疫苗的当前接种策略,并总结了当前推荐的疫苗。它评估了疫苗有效性和安全性的研究,并讨论了提高PLWH接种率的方法。使用关键词进行了系统研究。我们阐述了当前的知识状态,并突出了未来研究和开发的领域。

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