Qiu Yuqi, Park Sungjoon, Oszczapinska Urszula, Heller Laurie M
School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, United States.
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, United States.
Front Psychol. 2025 Aug 5;16:1569598. doi: 10.3389/fpsyg.2025.1569598. eCollection 2025.
Misophonia is a condition typically described as heightened intolerance to specific everyday sounds, although intense emotional and physiological responses can also be triggered by non-auditory representations of the sources of these sounds, e.g., words, videos, or imagination (Swedo et al., 2022). We asked whether pupillometry could provide an objective pupillary signature of the reactions of disgust and anger toward misophonic events depicted in movies. We found greater pupil constriction toward movies with more visually disgusting video tracks, both for misophonic and non-misophonic individuals, whereas movies with a video track suggesting a neutral source of a misophonic sound (e.g., Samermit et al., 2022, Heller et al., 2025) increased both the sound pleasantness ratings and the pupil diameters. Furthermore, repeated exposure to the same sounds in different movies changed pupil responses such that they diverged from the ratings of sound unpleasantness. The findings of this study may provide valuable insights into the understanding, diagnosis, and treatment of misophonia.
恐音症通常被描述为对特定日常声音的高度不耐受，尽管这些声音来源的非听觉表征（如文字、视频或想象）也可能引发强烈的情绪和生理反应（斯韦多等人，2022年）。我们询问瞳孔测量法是否能为对电影中描绘的恐音事件产生的厌恶和愤怒反应提供客观的瞳孔特征。我们发现，对于恐音症患者和非恐音症患者来说，观看具有更多视觉上令人厌恶的视频片段的电影时，瞳孔收缩幅度更大，而具有暗示恐音声音中性来源的视频片段的电影（如萨默米特等人，2022年；赫勒等人，2025年）则提高了声音愉悦度评分和瞳孔直径。此外，在不同电影中反复接触相同声音会改变瞳孔反应，使其与声音不愉快度评分产生分歧。本研究结果可能为恐音症的理解、诊断和治疗提供有价值的见解。
