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本文引用的文献

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2
Targeted therapy or immunotherapy in BRAF-mutated metastatic melanoma: a Spanish center's decade of experience.BRAF 突变转移性黑色素瘤的靶向治疗或免疫治疗:西班牙一家中心的十年经验
Front Oncol. 2024 Feb 21;14:1322116. doi: 10.3389/fonc.2024.1322116. eCollection 2024.
3
Oncology nurses' experiences of providing emotional support for cancer patients: a qualitative study.肿瘤护理人员为癌症患者提供情感支持的经历:一项定性研究。
BMC Nurs. 2024 Jan 20;23(1):58. doi: 10.1186/s12912-024-01718-1.
4
CAR-T cell manufacturing: Major process parameters and next-generation strategies.CAR-T 细胞生产:主要工艺参数和下一代策略。
J Exp Med. 2024 Feb 5;221(2). doi: 10.1084/jem.20230903. Epub 2024 Jan 16.
5
Inositol phosphatase INPP4B sustains ILC1s and intratumoral NK cells through an AKT-driven pathway.肌醇磷酸酶 INPP4B 通过 AKT 驱动的途径维持 ILC1s 和肿瘤内 NK 细胞。
J Exp Med. 2024 Mar 4;221(3). doi: 10.1084/jem.20230124. Epub 2024 Jan 10.
6
Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation.推进纳米技术以改善癌症靶向治疗:克服其临床实施中的障碍。
Mol Cancer. 2023 Oct 9;22(1):169. doi: 10.1186/s12943-023-01865-0.
7
The Future of Precision Oncology.精准肿瘤学的未来。
Int J Mol Sci. 2023 Aug 9;24(16):12613. doi: 10.3390/ijms241612613.
8
An oncolytic virus-delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment.溶瘤病毒递送的 TGFβ 抑制剂克服了免疫抑制性肿瘤微环境。
J Exp Med. 2023 Oct 2;220(10). doi: 10.1084/jem.20230053. Epub 2023 Aug 8.
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Nature. 2023 Mar;615(7953):687-696. doi: 10.1038/s41586-022-05531-1. Epub 2022 Nov 10.
10
Ethical issues in oncology practice: a qualitative study of stakeholders' experiences and expectations.肿瘤学实践中的伦理问题:利益相关者的经验和期望的定性研究。
BMC Med Ethics. 2022 Jun 30;23(1):67. doi: 10.1186/s12910-022-00803-x.

肿瘤学的治疗突破:加强治疗与管理。

Therapeutic breakthroughs in oncology: Enhancing treatment and management.

作者信息

Eskandar Kirolos

机构信息

Kirolos Eskandar, Diakonie Klinik Mosbach - Germany.

出版信息

Can Oncol Nurs J. 2025 Jul 1;35(4):590-605. doi: 10.5737/23688076354590. eCollection 2025.

DOI:10.5737/23688076354590
PMID:40873601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12379890/
Abstract

Recent advancements in oncology have significantly transformed cancer treatment and care management, offering new hope to patients worldwide. This literature review examines key therapeutic breakthroughs, including targeted therapies, immunotherapies, personalized medicine, and innovative drug delivery systems. These cutting-edge interventions have enhanced patient outcomes, improving survival rates and quality of life, but they have also introduced complexities in managing emerging side effects, care coordination, and resource allocation. This review discusses the implications of these therapies on patient care, the ethical considerations they entail, the management of side effects, and the pivotal role of oncology nurses in administering and managing these treatments. By exploring the current landscape and future directions of oncology therapies, including areas such as cancer vaccines and precision medicine, this article provides a comprehensive understanding of how these innovations are shaping the future of cancer care.

摘要

肿瘤学领域的最新进展显著改变了癌症治疗和护理管理,为全球患者带来了新的希望。这篇文献综述探讨了关键的治疗突破,包括靶向治疗、免疫治疗、个性化医疗以及创新的药物递送系统。这些前沿干预措施改善了患者的治疗效果,提高了生存率和生活质量,但同时也在管理新出现的副作用、护理协调和资源分配方面带来了复杂性。本综述讨论了这些疗法对患者护理的影响、所涉及的伦理考量、副作用的管理以及肿瘤学护士在实施和管理这些治疗中的关键作用。通过探索肿瘤学疗法的当前状况和未来方向,包括癌症疫苗和精准医学等领域,本文全面阐述了这些创新如何塑造癌症护理的未来。