Macekova Zuzana, Krivosova Michaela, Hudakova Nikola, Dragasek Jozef, Hajduk Michal, Zufkova Viera, Klimas Jan, Snopkova Miroslava
Department of Pharmacy and Social Pharmacy, University of Veterinary Medicine and Pharmacy in Kosice, Kosice, Slovakia.
Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia.
Front Public Health. 2025 Aug 12;13:1606381. doi: 10.3389/fpubh.2025.1606381. eCollection 2025.
Cognitive impairment (CI) is a growing public health problem. Our study is based on the fact that cognitive assessment in community pharmacy focused on early identification of undiagnosed CI has received limited attention. As pharmacists are the most accessible health professionals due to the availability of community pharmacies to the public, they have the potential to bring improvement in this area. Early identification of at-risk patients with CI by performing cognitive testing within advanced pharmaceutical care may improve the availability of targeted physician-indicated treatment.
The study is a multicentric study that will include cognitive screening within pharmaceutical care. We will use the Slovak version of the short form of the Montreal Cognitive Assessment (s-MoCA) test. Study participants will be at-risk patients undergoing cognitive screening in community pharmacies. Secondarily, we will evaluate the risk factors related to CI, such as at-risk medication use and modifiable dementia risk factors (e.g., cardiovascular and mental comorbidities, aging, and lifestyle habits).
This study was approved by the Ethics Committee of the Faculty of Pharmacy, Comenius University Bratislava (Ethics Committee Statement 01/2024). All procedures follow the relevant guidelines and regulations and the Declaration of Helsinki.
认知障碍(CI)是一个日益严重的公共卫生问题。我们的研究基于这样一个事实,即社区药房中专注于早期识别未确诊认知障碍的认知评估受到的关注有限。由于社区药房对公众开放,药剂师是最易接触到的医疗专业人员,他们有潜力在这一领域带来改善。通过在高级药学服务中进行认知测试,早期识别有认知障碍风险的患者,可能会提高有针对性的医生指示治疗的可及性。
该研究是一项多中心研究,将包括药学服务中的认知筛查。我们将使用蒙特利尔认知评估量表简版(s-MoCA)的斯洛伐克语版本进行测试。研究参与者将是在社区药房接受认知筛查的有风险患者。其次,我们将评估与认知障碍相关的风险因素,如使用有风险的药物以及可改变的痴呆风险因素(如心血管和精神合并症、衰老和生活方式习惯)。
本研究已获得布拉迪斯拉发夸美纽斯大学药学院伦理委员会的批准(伦理委员会声明01/2024)。所有程序均遵循相关指南和法规以及《赫尔辛基宣言》。