揭示DNA修复的作用机制：光笼化糖基化酶复合物的结构洞察
Illuminating DNA repair in action: structural insights into a photocaged glycosylase complex.
作者信息
Suga Michihiro
机构信息
Research Institute for Interdisciplinary Science, Okayama University, Okayama 700-8530, Japan.
出版信息
IUCrJ. 2025 Sep 1;12(Pt 5):513-514. doi: 10.1107/S2052252525007353.
PMID:40874471
Abstract
Structural analysis of the co-crystal between human DNA glycosylase hOGG1 and a light-sensitive substrate analog highlights its utility as a platform for real-time observation of catalytic dynamics.
摘要
人类DNA糖基化酶hOGG1与光敏感底物类似物共晶体的结构分析突出了其作为实时观察催化动力学平台的实用性。
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