Netsere Mehariw Wondim, Ayalew Zekarias Seifu, Belay Wubalem, Benti Henok, Bacha Seifu, Meselu Anteneh, Haile Asteway Mulat, Belay Kibret Enyew
Department of Internal Medicine, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Department of Internal Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
BMC Cardiovasc Disord. 2025 Aug 28;25(1):638. doi: 10.1186/s12872-025-05102-y.
Brugada syndrome is an autosomal dominant inherited disorder that is generally rare but can potentially cause life-threatening arrhythmia, sudden cardiac arrest, or death in young adults with structurally normal hearts. It is characterized by coved-type ST-segment elevation with T-wave inversion and with or without a right bundle branch block.
A 42-year-old Ethiopian man presented with two episodes of loss of consciousness followed by palpitations and experienced documented in-hospital cardiac arrest due to ventricular tachycardia, which was successfully resuscitated. A diagnosis of Brugada syndrome was made after a typical electrocardiogram finding was noted postresuscitation.
Although rare, Brugada syndrome is not nonexistent in the Black population, and it should be considered in young adults presenting with syncope, sudden cardiac arrest, or death in otherwise structurally normal hearts.
Brugada综合征是一种常染色体显性遗传性疾病，通常较为罕见，但在心脏结构正常的年轻成年人中可能会导致危及生命的心律失常、心脏骤停或死亡。其特征为伴有T波倒置的穹窿型ST段抬高，伴或不伴有右束支传导阻滞。
一名42岁的埃塞俄比亚男子出现两次意识丧失，随后心悸，并在医院记录到因室性心动过速导致的心脏骤停，经成功复苏。复苏后发现典型心电图表现，从而诊断为Brugada综合征。
尽管罕见，但Brugada综合征在黑人人群中并非不存在，对于出现晕厥、心脏骤停或在其他方面心脏结构正常但却死亡的年轻成年人，应考虑该疾病。
