Watanabe Manami, Fujimura Taku, Asano Yoshihide
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Case Rep Oncol. 2025 Feb 12;18(1):325-329. doi: 10.1159/000544164. eCollection 2025 Jan-Dec.
Among the spectrum of mycosis fungoides (MF), poikilodermatous MF (PMF) is a rare clinical variant of patch-stage MF, which is characterized by cutaneous atrophy, mottled-reticular pigmentation, and telangiectasia. Given its favorable prognosis, ultraviolet (UV) light therapy, such as narrowband UVB (NB-UVB), is commonly employed for the treatment of PMF. Notably, the 308-nm excimer laser emits high-energy monochromatic light with a wavelength close to the NB-UVB peak.
Herein, we report a case of PMF successfully treated with the 308-nm excimer laser.
There have been no English-language case reports describing the use of excimer laser treatment for PMF, and this is the first English report that suggests the usefulness of the 308-nm excimer laser for the treatment of PMF, which is one of the clinical variants of patch-stage of MF.
在蕈样肉芽肿（MF）谱系中，皮肤异色病样MF（PMF）是斑块期MF的一种罕见临床变异型，其特征为皮肤萎缩、斑驳状网状色素沉着和毛细血管扩张。鉴于其预后良好，紫外线（UV）光疗，如窄谱中波紫外线（NB-UVB），常用于治疗PMF。值得注意的是，308纳米准分子激光发射的高能单色光波长接近NB-UVB峰值。
在此，我们报告一例成功使用308纳米准分子激光治疗的PMF病例。
尚无英文病例报告描述准分子激光治疗PMF的情况，这是首份英文报告，提示308纳米准分子激光对治疗PMF（MF斑块期的临床变异型之一）有用。
