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[克罗恩病的手术指征及预后,特别涉及肛门病变的处理]

[Surgical indication and outcome of Crohn's disease with special reference to management of anal lesions].

作者信息

Muto T, Konishi F, Sawada T, Morioka Y, Kanazawa K, Yamamoto T, Shida H

出版信息

Nihon Geka Gakkai Zasshi. 1985 Sep;86(9):1316-9.

PMID:4088263
Abstract

A total of 31 cases of Crohn's disease; 23 males and 8 females; 8 small bowel, 11 colon, 8 both small and large bowels involvement and 4 unknown, were collected and analysed. Twelve cases were treated medically and 19 were operated with 61% of operative and 37% of reoperative rate. There was no death due to Crohn's disease. IVH was successful as non-surgical treatment. Indications for surgery were stricture, fistula formation and unsuccessful medical treatment. Limited resection of the diseased segment was performed and in 4 cases diseased segment was left behind without significant postoperative symptoms. Quality of life of the surgically and medically treated patients was satisfactory except one who had many operations during 20 years and still suffers from Crohn's disease. In 15 (48.4%) periproctal abscess or fistula was associated. There were 2 types of anal lesions, the one being ordinary type of low intersphincteric abscess or fistula and the other complex or Crohn's disease related high abscess or fistula. The former was successfully treated by laying-open whereas the latter was treated rather conservatively by drainage not to damage external sphincter muscles. Outcome of medical and surgical treatment of Crohn's disease was quite satisfactory and operation should not be hesitated in patients with serious complications. Type of anal lesion is to be identified and proper surgical treatment should be performed in feasible cases.

摘要

共收集并分析了31例克罗恩病患者,其中男性23例,女性8例;病变累及小肠8例,结肠11例,小肠和结肠均受累8例,部位不明4例。12例接受药物治疗,19例接受手术治疗,手术率为61%,再次手术率为37%。无因克罗恩病死亡病例。静脉内高营养作为非手术治疗取得成功。手术指征为狭窄、瘘管形成及药物治疗无效。对病变肠段进行有限切除,4例未切除病变肠段,术后无明显症状。除1例在20年间接受多次手术仍患有克罗恩病外,手术治疗和药物治疗患者的生活质量均令人满意。15例(48.4%)伴有肛周脓肿或肛瘘。肛门病变有2种类型,一种是普通型低位括约肌间脓肿或肛瘘,另一种是复杂型或与克罗恩病相关的高位脓肿或肛瘘。前者采用切开引流成功治愈,后者采用引流治疗较为保守,以免损伤外括约肌。克罗恩病的药物和手术治疗效果相当令人满意,对于有严重并发症的患者不应犹豫进行手术。应明确肛门病变类型,在可行的情况下进行适当的手术治疗。

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