Krüger N, Kraus C, Tillmann W, Schröter W
Monatsschr Kinderheilkd. 1985 Dec;133(12):876-8.
Antibodies against Yersinia were found in 12 of 50 patients with hemosiderosis, in 11 of 47 patients with thalassemia major and in one of three patients with Blackfan-Diamond anemia. All patients were treated with subcutaneous continuous deferoxamin-infusions. A systemic yersiniosis occurred in seven patients, all with homozygous beta-thalassemia, in five during and in two before treatment with deferoxamin. Hemosiderosis and infusions with deferoxamin seem to increase the risk of yersinia septicemia.
在50例含铁血黄素沉着症患者中，有12例检测出抗耶尔森菌抗体；在47例重型地中海贫血患者中，有11例检测出抗耶尔森菌抗体；在3例先天性纯红细胞再生障碍性贫血患者中，有1例检测出抗耶尔森菌抗体。所有患者均接受皮下持续去铁胺输注治疗。7例患者发生了全身性耶尔森菌病，均为纯合子β地中海贫血患者，其中5例在接受去铁胺治疗期间发病，2例在治疗前发病。含铁血黄素沉着症和去铁胺输注似乎会增加耶尔森菌败血症的风险。
