用于尸体腕关节造影并采用附加锡滤过器降低剂量的光子计数CT与能量积分探测器及平板CT的比较
Photon-counting CT versus energy-integrating detector and flat-panel CT for cadaveric wrist arthrography with additional tin filter dose reduction.
作者信息
de Boer Johannes, Salimova Nigar, Weidemann Friederike, Behrendt Lea, Werncke Thomas, Wacker Frank K, Sonnow Lena
机构信息
Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Department of Trauma Surgery, Hannover Medical School, Hannover, Germany.
出版信息
Eur Radiol Exp. 2025 Aug 29;9(1):83. doi: 10.1186/s41747-025-00604-y.
BACKGROUND
This study aimed to evaluate the imaging performance and diagnostic value of a photon-counting detector (PCD) computed tomography (CT) compared to an energy-integrating detector (EID) and flat panel detector (FPD) for cadaveric wrist arthrographies.
METHODS
Following ethics committee approval, ten cadaveric wrists were injected with diluted iodinated contrast agent. CT arthrographies using PCD-, EID-, and FPD-CT were performed. Six dose protocols between 0.1 mGy (using a tin filter) and 6 mGy, ultrahigh-resolution-mode, and two reconstruction kernels were used for the PCD-CT and EID-CT. FPD-CT images were reconstructed using a "normal" and "sharp" kernel. Signal-to-noise ratios (SNR) and contrast-to-noise ratios (CNR) were calculated and analyzed using analysis of variance (ANOVA) and post hoc tests. Three blinded radiologists independently rated image quality concerning trabecular, cartilage, and intrinsic structures. Intraclass correlation coefficients (ICC) were calculated, followed by a Friedman and post hoc test.
RESULTS
At 1.5 mGy, 3 mGy, and 6 mGy with the Br89 kernel, the PCD-CT yielded up to 2.35 times higher SNR and up to 7 times higher CNR than dose-equivalent and higher dose EID-CT scans. Subjective ratings favored the PCD-CT over the EID-CT and occasionally the FPD-CT, with a combined ICC of 0.942. Applying sharper kernels, SNR did not differ significantly between the PCD-CT (1.5 mGy, 3 mGy, and 6 mGy) and the FPD-CT.
CONCLUSION
Using sharp kernels, the PCD-CT provided superior image quality to the EID-CT and achieved comparable or better quality than the FPD at certain parameters. Thus, the PCD-CT could be considered a possible alternative in clinical routine for evaluating wrist injuries.
RELEVANCE STATEMENT
This study demonstrates the potential of the PCD-CT as a valuable tool in diagnosing wrist injuries. Its superior image quality compared to the EID-CT can increase confidence in diagnosing subtle bone pathologies and additionally yields the possibility of radiation exposure reduction.
KEY POINTS
The technical advantages of the PCD-CT allow for dose reduction while generating high-quality images. PCD-CT showed superior image quality over EID-CT and was comparable to the FPD-CT. PDC-CT offers improved visualization of fine joint structures in wrist arthrography and should be considered in clinical routine.
背景
本研究旨在评估光子计数探测器(PCD)计算机断层扫描(CT)与能量积分探测器(EID)和平板探测器(FPD)相比,在尸体腕关节造影中的成像性能和诊断价值。
方法
经伦理委员会批准后,向10具尸体腕关节注射稀释的碘化造影剂。使用PCD-CT、EID-CT和FPD-CT进行关节造影CT检查。PCD-CT和EID-CT采用0.1 mGy(使用锡滤过器)至6 mGy之间的6种剂量方案、超高分辨率模式和两种重建核。FPD-CT图像使用“正常”和“锐利”核进行重建。使用方差分析(ANOVA)和事后检验计算并分析信噪比(SNR)和对比噪声比(CNR)。三名盲法放射科医生独立对小梁、软骨和固有结构的图像质量进行评分。计算组内相关系数(ICC),随后进行Friedman检验和事后检验。
结果
在1.5 mGy、3 mGy和6 mGy剂量下,使用Br89核时,PCD-CT产生的SNR比剂量相当及更高剂量的EID-CT扫描高2.35倍,CNR高7倍。主观评分显示PCD-CT优于EID-CT,偶尔也优于FPD-CT,综合ICC为0.942。应用更锐利的核时,PCD-CT(1.5 mGy、3 mGy和6 mGy)与FPD-CT之间的SNR无显著差异。
结论
使用锐利核时,PCD-CT提供的图像质量优于EID-CT,在某些参数下与FPD相当或更好。因此,在临床常规评估腕部损伤时,PCD-CT可被视为一种可能的替代方法。
相关性声明
本研究证明了PCD-CT作为诊断腕部损伤的有价值工具的潜力。与EID-CT相比,其优越的图像质量可提高对细微骨病变诊断的信心,并有可能减少辐射暴露。
关键点
PCD-CT的技术优势允许在生成高质量图像的同时降低剂量。PCD-CT显示出优于EID-CT的图像质量,与FPD-CT相当。PCD-CT在腕关节造影中能更好地显示精细的关节结构,应在临床常规中予以考虑。