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"Tamoxifen for residual NF-PitNETs: A Proof-of-Concept study integrating receptor profiling, pilot trial, and target pathway analysis".

作者信息

Haydar Ali Tajuddin Amalina, Sukor Norlela, Azizan Elena Aisha, Kamaruddin Nor Azmi, Omar Ahmad Marzuki, Tan Geok Chin, Mustangin Muaatamarulain, Alias Azmi, Wan Ismail Wan Ruza Iswati, Abd Latif Kartikasalwah, Idris Nurdillah, Uddin Md Nazim, Rullah Kamal, Isa Nur Firdaus, Mohd Nasir Mohd Hamzah

机构信息

Department of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan Campus, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Kuantan, 25200, Pahang, Malaysia.

Medical Department, Faculty of Medicine, National University of Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, 56000, Malaysia.

出版信息

Endocrine. 2025 Sep 1. doi: 10.1007/s12020-025-04404-7.

DOI:10.1007/s12020-025-04404-7
PMID:40889098
Abstract
摘要

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本文引用的文献

1
Identification of cholesterol metabolism-related subtypes in nonfunctioning pituitary neuroendocrine tumors and analysis of immune infiltration.鉴定无功能垂体神经内分泌肿瘤中的胆固醇代谢相关亚型，并分析免疫浸润情况。
Lipids Health Dis. 2023 Aug 10;22(1):127. doi: 10.1186/s12944-023-01883-3.
2
The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas-New Potential Therapeutic Approach-A Systematic Review.PI3K/AKT/mTOR 和 RAF/MEK/ERK 通路激活在侵袭性垂体腺瘤中的作用——新的潜在治疗方法——系统评价。
Int J Mol Sci. 2023 Jun 30;24(13):10952. doi: 10.3390/ijms241310952.
3
Pituitary Tumorigenesis-Implications for Management.
垂体肿瘤发生-对治疗的影响。
Medicina (Kaunas). 2023 Apr 21;59(4):812. doi: 10.3390/medicina59040812.
4
Comparative Efficacy of AZD9496 and Fulvestrant on the Growth of Pituitary Adenoma via Blocking JAK2/STAT5B Pathway.AZD9496与氟维司群通过阻断JAK2/STAT5B通路对垂体腺瘤生长的疗效比较
J Cancer. 2023 Jan 1;14(1):61-71. doi: 10.7150/jca.79726. eCollection 2023.
5
Evaluating the expression pattern of the opioid receptor in pituitary neuroendocrine tumors (PitNET) and the role of morphine and naloxone in the regulation of pituitary cell line growth and apoptosis.评估阿片受体在垂体神经内分泌肿瘤（PitNET）中的表达模式以及吗啡和纳洛酮在调节垂体细胞系生长和凋亡中的作用。
Biomed Pharmacother. 2023 Jan;157:114022. doi: 10.1016/j.biopha.2022.114022. Epub 2022 Nov 19.
6
Tamoxifen Exerts Anticancer Effects on Pituitary Adenoma Progression via Inducing Cell Apoptosis and Inhibiting Cell Migration.他莫昔芬通过诱导细胞凋亡和抑制细胞迁移发挥对垂体腺瘤进展的抗癌作用。
Int J Mol Sci. 2022 Feb 28;23(5):2664. doi: 10.3390/ijms23052664.
7
Characteristic of Tumor Regrowth After Gamma Knife Radiosurgery and Outcomes of Repeat Gamma Knife Radiosurgery in Nonfunctioning Pituitary Adenomas.伽玛刀放射外科治疗后无功能垂体腺瘤的肿瘤再生长特征及重复伽玛刀放射外科治疗的结果
Front Oncol. 2021 Mar 5;11:627428. doi: 10.3389/fonc.2021.627428. eCollection 2021.
8
Estrogen Receptors in Nonfunctioning Pituitary Neuroendocrine Tumors: Review on Expression and Gonadotroph Functions.无功能垂体神经内分泌肿瘤中的雌激素受体：表达与促性腺激素细胞功能综述
J Endocr Soc. 2020 Oct 19;4(12):bvaa157. doi: 10.1210/jendso/bvaa157. eCollection 2020 Dec 1.
9
Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT-20 and TtT/GF by affecting expression of MMP-14 and ADAM12.选择性雌激素受体调节剂通过影响 MMP-14 和 ADAM12 的表达来降低垂体腺瘤细胞系 AtT-20 和 TtT/GF 的侵袭性。
FEBS Open Bio. 2020 Nov;10(11):2489-2498. doi: 10.1002/2211-5463.12999. Epub 2020 Oct 26.
10
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Life Sci. 2020 Nov 1;260:118416. doi: 10.1016/j.lfs.2020.118416. Epub 2020 Sep 11.