Millar D S, Davis L R, Rodeck C H, Nicolaides K H, Mibashan R S
Prenat Diagn. 1985 Nov-Dec;5(6):367-73. doi: 10.1002/pd.1970050602.
Samples of pure fetal blood from 116 fetuses of 15-21 weeks' gestation were obtained by direct vision fetoscopy. Ninety nine of these fetuses, presumed to be haematologically normal, were suitable for analysis. The data obtained show that the erythropoietic system is evolving rapidly in this gestational age range. The myeloid series shows no significant increase or decrease in numbers apart from eosinophils and basophils which increase significantly with gestational age whereas the platelet count remains constant. The growing application of fetoscopic blood sampling to the prenatal diagnosis and management of fetal blood disorders renders mandatory a knowledge of normal fetal blood values.
通过直视胎儿镜从116例妊娠15 - 21周的胎儿获取了纯胎儿血样本。其中99例胎儿推测血液学正常，适合进行分析。所获得的数据表明，在这个孕周范围内，红细胞生成系统正在迅速发育。除嗜酸性粒细胞和嗜碱性粒细胞随孕周显著增加外，髓系细胞数量无显著增减，而血小板计数保持恒定。胎儿镜下采血在胎儿血液疾病的产前诊断和管理中的应用日益广泛，因此必须了解正常胎儿血液值。
