Khan Farheen, Noronha Roxanne, Williams Sara, Satgunalingam Anojan, Wong-Riff Karen W Y, Ali Asim, Dimaras Helen
Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada.
Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
Eye (Lond). 2025 Sep 1. doi: 10.1038/s41433-025-03969-x.
BACKGROUND/OBJECTIVES: FACE-Q Craniofacial Module is a validated patient-reported outcome measure for appearance. This study aimed to assess the content validity of FACE-Q Craniofacial Module for use in patients treated for corneal anaesthesia.
SUBJECTS/METHODS: This was a qualitative, prospective observational study. Cognitive debriefing interviews were conducted with patients ≥8 years old who had surgical treatment for corneal anaesthesia at least six months before time of study. Two rounds of interviews gathered feedback on the comprehensibility, comprehensiveness, and relevance of three eye scales and checklists and four health-related quality-of-life scales. Based on the input from participants, ophthalmologists, scientists, and patient advocates, the scales and checklists were modified, then further refined.
Feedback on the FACE-Q scales and checklists was obtained from 10 participants. Instructions for the scales were modified to enhance comprehensibility. Eleven items were revised for enhanced comprehensibility and relevance. Twelve items were added to enhance comprehensiveness. Four items were removed due to their irrelevance to appearance or corneal anaesthesia. Modifications to the eye and health-related quality-of-life scales were generally condition-specific and generic, respectively. A comment section was added to the end of each scale and checklist.
The FACE-Q demonstrates strong potential for adaptation to measure appearance outcomes in corneal anaesthesia patients. With lived expertise, clinical, and scientific input, the content validity of FACE-Q was improved for use in corneal anaesthesia patients. The modified FACE-Q is now ready for psychometric evaluation and further validation. Meeting Presentations: Poster Presentation at 2023 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting in New Orleans, LA, April 23-27, 2023.
背景/目的：面部质量问卷（FACE-Q）颅面部模块是一种经过验证的用于评估外观的患者报告结局指标。本研究旨在评估FACE-Q颅面部模块在角膜麻醉治疗患者中的内容效度。
受试者/方法：这是一项定性的前瞻性观察性研究。对在研究前至少六个月接受过角膜麻醉手术治疗的8岁及以上患者进行认知性深入访谈。两轮访谈收集了关于三个眼部量表和检查表以及四个健康相关生活质量量表的可理解性、全面性和相关性的反馈。根据参与者、眼科医生、科学家和患者倡导者的意见，对量表和检查表进行了修改，然后进一步完善。
从10名参与者那里获得了关于FACE-Q量表和检查表的反馈。修改了量表的说明以提高可理解性。对11个项目进行了修订以提高可理解性和相关性。增加了12个项目以提高全面性。由于与外观或角膜麻醉无关，删除了4个项目。眼部量表和健康相关生活质量量表的修改通常分别针对特定情况和一般情况。在每个量表和检查表的末尾添加了一个评论部分。
FACE-Q在用于测量角膜麻醉患者的外观结局方面显示出很强的适应性潜力。通过实际经验、临床和科学方面的投入，FACE-Q在用于角膜麻醉患者时的内容效度得到了提高。经过修改的FACE-Q现在已准备好进行心理测量评估和进一步验证。会议报告：2023年4月23日至27日在路易斯安那州新奥尔良举行的2023年视觉与眼科学研究协会（ARVO）年会上的海报展示。
