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Huangqi Guizhi Wuwu Decoction inhibits ferroptosis to improve cyclophosphamide induced immunosuppression through regulation of arachidonic acid metabolism.

作者信息

Wang Li, Liu Fenyun, Wan Qianqian, Xia Yafei, Zhang Qi, Xun Jing, Li Ping, Wang Yuming, Li Mei, Bian Yuhong, Cui Huantian

机构信息

Tianjin University, Tianjin, 300072, China.

Department of Pharmacy, Tianjin Second People's Hospital, Tianjin, 300192, China.

出版信息

J Mol Histol. 2025 Sep 2;56(5):289. doi: 10.1007/s10735-025-10582-5.

DOI:10.1007/s10735-025-10582-5
PMID:40892292
Abstract
摘要

相似文献

1
Huangqi Guizhi Wuwu Decoction inhibits ferroptosis to improve cyclophosphamide induced immunosuppression through regulation of arachidonic acid metabolism.黄芪桂枝五物汤通过调节花生四烯酸代谢抑制铁死亡以改善环磷酰胺诱导的免疫抑制。
J Mol Histol. 2025 Sep 2;56(5):289. doi: 10.1007/s10735-025-10582-5.
2
Study on efficacy and safety of Huangqi Guizhi Wuwu decoction treatment for oxaliplatin induced peripheral neurotoxicity: A protocol for a randomized, controlled, double-blind, multicenter trial.黄芪桂枝五物汤治疗奥沙利铂所致周围神经毒性的有效性和安全性研究：一项随机、对照、双盲、多中心试验方案
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RNA-seq revealed the protective effect of Huangqi Guizhi Wuwu Decoction against cisplatin induced PC12 cell injury.RNA测序揭示了黄芪桂枝五物汤对顺铂诱导的PC12细胞损伤的保护作用。
Int J Neurosci. 2024 Aug 19:1-11. doi: 10.1080/00207454.2024.2392123.
4
Efficacy and Safety of Huangqi Guizhi Wuwu Decoction for Oxaliplatin-Induced Peripheral Neurotoxicity: A Systematic Review and Meta-Analysis.黄芪桂枝五物汤治疗奥沙利铂所致周围神经毒性的疗效和安全性的系统评价和荟萃分析。
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Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathway.黄芪桂枝五物汤通过 TNFα/IL-1β/IL-6/MAPK/NF-κB 通路防治奥沙利铂所致神经病理性疼痛。
Aging (Albany NY). 2022 Jun 27;14(12):5013-5022. doi: 10.18632/aging.203794.
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[Research progress on Huangqi Guizhi Wuwu Decoction and predictive analysis of quality markers].[黄芪桂枝五物汤研究进展及质量标志物预测分析]
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The efficacy and safety of Huangqi Guizhi Wuwu decoction for rheumatoid arthritis: A protocol for systematic review and meta-analysis.黄芪桂枝五物汤治疗类风湿关节炎的疗效与安全性：系统评价与Meta分析方案
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[UPLC-Q-TOF-MS analysis on chemical constituents of classical prescription Huangqi Guizhi Wuwu Tang standard decoction].经典方剂黄芪桂枝五物汤标准汤剂化学成分的超高效液相色谱-四极杆飞行时间质谱分析
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Huangqi Guizhi Wuwu decoction ameliorates myocardial damage in ovariectomized rats by regulating the structure and function of myocardial microvessels and intestinal flora.黄芪桂枝五物汤通过调节心肌微血管结构和功能以及肠道菌群来改善去卵巢大鼠的心肌损伤。
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Huangqi Guizhi Wuwu Decoction Improves Inflammatory Factor Levels in Chemotherapy-induced Peripheral Neuropathy by Regulating the Arachidonic Acid Metabolic Pathway.黄芪桂枝五物汤通过调节花生四烯酸代谢通路改善化疗所致周围神经病变的炎症因子水平。
Curr Pharm Des. 2024;30(34):2701-2717. doi: 10.2174/0113816128308622240709102830.

本文引用的文献

1
Interplay of disulfidptosis and the tumor microenvironment across cancers: implications for prognosis and therapeutic responses.二硫化物诱导细胞焦亡与肿瘤微环境在多种癌症中的相互作用：对预后和治疗反应的影响
BMC Cancer. 2025 Jul 1;25(1):1113. doi: 10.1186/s12885-025-14246-1.
2
Research progress on the cross-regulation between ferroptosis and immunogenic cell death in tumor micro-environment.肿瘤微环境中细胞铁死亡与免疫原性细胞死亡交叉调控的研究进展
Front Oncol. 2025 Jun 4;15:1581951. doi: 10.3389/fonc.2025.1581951. eCollection 2025.
3
Splenic comparative transcriptome analysis reveals the immunological mode of undomesticated Gayal (Bos frontalis) for adapting to harsh environments.
脾脏比较转录组分析揭示了野牛（Bos frontalis）适应恶劣环境的免疫模式。
BMC Genomics. 2025 May 21;26(1):514. doi: 10.1186/s12864-025-11718-3.
4
The Role of PLIN3 in Prognosis and Tumor-Associated Macrophage Infiltration: A Pan-Cancer Analysis.PLIN3在预后及肿瘤相关巨噬细胞浸润中的作用：一项泛癌分析
J Inflamm Res. 2025 Mar 13;18:3757-3777. doi: 10.2147/JIR.S509245. eCollection 2025.
5
Comprehensive pan-cancer analysis reveals EPHB2 is a novel predictive biomarker for prognosis and immunotherapy response.全面泛癌分析揭示 EphB2 是一种新的预测预后和免疫治疗反应的生物标志物。
BMC Cancer. 2024 Aug 28;24(1):1064. doi: 10.1186/s12885-024-12843-0.
6
Cyclophosphamide induces ovarian granulosa cell ferroptosis via a mechanism associated with HO-1 and ROS-mediated mitochondrial dysfunction.环磷酰胺通过与 HO-1 和 ROS 介导的线粒体功能障碍相关的机制诱导卵巢颗粒细胞发生铁死亡。
J Ovarian Res. 2024 May 18;17(1):107. doi: 10.1186/s13048-024-01434-z.
7
Ironing out the role of ferroptosis in immunity.消除铁死亡在免疫中的作用。
Immunity. 2024 May 14;57(5):941-956. doi: 10.1016/j.immuni.2024.03.019.
8
Construction and validation of a hypoxia-related gene signature to predict the prognosis of breast cancer.构建并验证一个与缺氧相关的基因特征，以预测乳腺癌的预后。
BMC Cancer. 2024 Apr 1;24(1):402. doi: 10.1186/s12885-024-12182-0.
9
Differences in Immune Characteristics and Related Gene Expression in Spleen among Ningxiang, Berkshire Breeds and Their Hybrid Pigs.宁乡猪、大约克夏猪及其杂种猪脾脏免疫特性及相关基因表达的差异。
Genes (Basel). 2024 Feb 4;15(2):205. doi: 10.3390/genes15020205.
10
The potential immunomodulatory effect of levamisole in humans and farm animals.左旋咪唑对人和家畜的潜在免疫调节作用。
J Adv Vet Anim Res. 2023 Dec 31;10(4):620-629. doi: 10.5455/javar.2023.j717. eCollection 2023 Dec.