Khan Lubna, Hasan Ahmad, Alvi Shakeel, Abbasi Maryam, Ali Rashid
Department of Chemistry, Jamia Millia Islamia, Jamia Nagar, Okhla, New Delhi, 110025, India.
Top Curr Chem (Cham). 2025 Sep 2;383(3):36. doi: 10.1007/s41061-025-00525-9.
In organic synthesis, named reactions are fundamental chemical conversions that fabricate invaluable molecules of high importance. Hence, a deep understanding of these vital reactions is a prerequisite from the organic chemistry point of view. Basically, the names of these chemical reactions are used as short forms to make it easier to talk or write in the realm of synthetic organic chemistry. Moreover, these vital chemical reactions are the background for understanding the fundamentals of organic chemistry and are robust chemical tools that attain intricacy in molecular architectures, which are otherwise daunting tasks or sometimes impossible to achieve. Therefore, keeping the importance of the organic named reactions in mind, herein, we have comprehensively detailed all literature reporting 50 named reactions taking place in deep eutectic solvents (DESs)-the eco-friendly reaction media. The authors are of the opinion that this systematic collection of such important reactions carried out under green reaction conditions will add value not only to organic syntheses but will also open new opportunities that expand the chemical space for other crucial reactions. Moreover, we believe that these all-in-one named reaction assortments will be very useful to undergraduate as well as postgraduate students, and obviously for Ph.D. scholars and the synthetic chemistry research community in general.
在有机合成中，命名反应是构建具有极高重要性的宝贵分子的基本化学转化过程。因此，从有机化学的角度来看，深入理解这些关键反应是一项先决条件。基本上，这些化学反应的名称被用作简称，以便在合成有机化学领域更轻松地进行交流或书写。此外，这些关键化学反应是理解有机化学基础的背景知识，并且是实现分子结构复杂性的强大化学工具，否则这些任务将艰巨无比，有时甚至无法完成。因此，鉴于有机命名反应的重要性，在此我们全面详细地介绍了所有报道在深共熔溶剂（DESs）——这种环境友好型反应介质中发生的50种命名反应的文献。作者认为，这种在绿色反应条件下对如此重要反应的系统收集不仅将为有机合成增添价值，还将开辟新的机会，拓展其他关键反应的化学空间。此外，我们相信这些一体化的命名反应合集对本科生和研究生都将非常有用，显然对博士学者以及整个合成化学研究群体也很有用。
