Cui Peicai, Lu Lehua, Wang Yuqing, Hua Qing, Zhang Ke, Gao Jie, Zhang Mingjian, Gao Yihan, Li Bin
Shanghai New Tobacco Product Research Institute Co., Ltd, Shanghai 201315, China.
Technology Center, Shanghai Tobacco Group Co., Ltd, Shanghai 201315, China.
ACS Omega. 2025 Aug 18;10(33):37702-37709. doi: 10.1021/acsomega.5c04261. eCollection 2025 Aug 26.
Puff-by-puff release stability is critical for heated tobacco product (HTP) quality and user experience, yet existing methods lack dynamic puff-by-puff evaluation. Here, we develop a novel stability index (SI) using the "modulus of the sum vector of two evaluation dimensions" algorithm to quantify puff-by-puff release consistency and interpuff variability. In addition, the algorithm has been validated through practical product applications. Compared with traditional methods, SI significantly enhances the differentiation and accuracy of stability evaluation. Under a 10% relative deviation in the release amount measurement, the deviation of the stability index (SI) is maintained at 10.6%, demonstrating precision. The SI is applicable to reconstituted tobacco sheets, HTP sticks, and final products, enabling quantitative stability assessment. As a key screening tool, it streamlines HTPs development by identifying inconsistent formulations early.
逐口释放稳定性对于加热烟草产品（HTP）的质量和用户体验至关重要，但现有方法缺乏逐口动态评估。在此，我们使用“两个评估维度的和向量模”算法开发了一种新型稳定性指数（SI），以量化逐口释放一致性和口间变异性。此外，该算法已通过实际产品应用得到验证。与传统方法相比，SI显著提高了稳定性评估的区分度和准确性。在释放量测量相对偏差为10%的情况下，稳定性指数（SI）的偏差保持在10.6%，显示出精确性。SI适用于再造烟叶、HTP烟支和最终产品，能够进行定量稳定性评估。作为一种关键的筛选工具，它通过早期识别不一致的配方简化了HTP的开发。
