多发性复发性难治性骨髓瘤中多灶性结肠肿物作为继发性髓外浆细胞瘤的一种表现：一例报告并文献复习
Multifocal Colonic Masses as a Presentation of Secondary Extramedullary Plasmacytoma in Relapsing-Refractory Multiple Myeloma: A Case Report and Review of Literature.
作者信息
Gaddipati Sirisha, Sandhu Sunny, Martin Eric F
机构信息
Department of Medicine University of Miami Miller School of Medicine Miami Florida USA.
Division of Digestive Health and Liver Diseases, Department of Medicine Miller School of Medicine at the University of Miami Miami Florida USA.
出版信息
JGH Open. 2025 Aug 29;9(9):e70239. doi: 10.1002/jgh3.70239. eCollection 2025 Sep.
BACKGROUND
Multiple myeloma (MM) is a common plasma cell malignancy; however, extramedullary multiple myeloma (EMM) is an aggressive phenotype in which malignant plasma cells proliferate outside of the bone marrow.
AIMS
Extramedullary plasmacytomas (EMP) are uncommon and gastrointestinal involvement is exceedingly rare.
CASE PRESENTATION
Here, we present a case of multifocal secondary colonic EMP in a patient with relapsed refractory multiple myeloma (RRMM) and review literature demonstrating other cases of secondary colonic EMP.
背景
多发性骨髓瘤（MM）是一种常见的浆细胞恶性肿瘤；然而，髓外多发性骨髓瘤（EMM）是一种侵袭性表型，其中恶性浆细胞在骨髓外增殖。
目的
髓外浆细胞瘤（EMP）并不常见，胃肠道受累极为罕见。
病例报告
在此，我们报告一例复发难治性多发性骨髓瘤（RRMM）患者发生多灶性继发性结肠EMP的病例，并回顾文献中显示的其他继发性结肠EMP病例。
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