Yester Jessie, Nandi Deipanjan
The Heart Center, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
JHLT Open. 2025 Aug 5;10:100358. doi: 10.1016/j.jhlto.2025.100358. eCollection 2025 Nov.
The management of pediatric heart failure and titration of oral medical therapies remains in its infancy. Burdened by a lack of understanding of the diverse pediatric heart failure etiologies, limitations in clinical trials, a lack of society guidelines, as well as other health care systemic issues, titration of medications is greatly lacking. We herein review the difficulties with medication titration in pediatric heart failure, and highlight important next steps to remedy the situation.
小儿心力衰竭的管理及口服药物治疗的滴定仍处于起步阶段。由于对小儿心力衰竭病因的多样性缺乏了解、临床试验存在局限性、缺乏社会指南以及其他医疗系统问题，药物滴定严重不足。我们在此回顾小儿心力衰竭药物滴定的困难，并强调改善这种情况的重要后续步骤。
